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Application
FIGURE: 1 / 4
TNN Antibody (PA5-55411) in IHC
Immunohistochemical staining of TNN in human salivary gland using TNN Polyclonal Antibody (Product # PA5-55411) shows weak cytoplasmic and moderate to strong membranous positivity in glandular cells.
Product Details
PA5-55411
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human TNN. Recombinant protein control fragment (Product #RP-94145).
Conjugate
Unconjugated
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2648789
Product Specific Information
Immunogen sequence: KEQQVTVSHT YKIDVPKSAL VQVDADPQPL SDDGASLLAL GEAREEQNII FRHNIRLQTP QKDCELAGSV QDLLARVKKL EEEMVEMKEQ CSA
Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 85%.
Target Information
Extracellular matrix protein that seems to be a ligand for ITGA8:ITGB1, ITGAV:ITGB1 and ITGA4:ITGB1 (PubMed:17909022). Involved in neurite outgrowth and cell migration in hippocampal explants. During endochondral bone formation, inhibits proliferation and differentiation of proteoblasts mediated by canonical WNT signaling. In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells (PubMed:19884327). Expressed in most mammary tumors, may facilitate tumorigenesis by supporting the migratory behavior of breast cancer cells (PubMed:17909022). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Tenascin-N; Tenascin-W; TN-N; TN-W
Gene Aliases: TN-W; TNN; TNW
UniProt ID: (Human) Q9UQP3
Entrez Gene ID: (Human) 63923
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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