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Sequence of this protein is as follows: MGSKASSPHG LGSPLVASPR LEKRLGGLAP QRGSRISVLS ASPVSDVSYM FGSSQSLLHS SNSSHQSSSR SLESPANSSS SLHSLGSVSL CTRPSDFQAP RNPTLTMGQP RTPHSPPLAK EHASSCPPSI TNSMVDIPIV LINGCPEPGS SPPQRTPGHQ NSVQPGAASP SNPCPATRSN SQTLSDAPFT TCPEGPARDM QPTMKFVMDT SKYWFKPNIT REQAIELLRK EEPGAFVIRD SSSYRGSFGL ALKVQEVPAS AQSRPGEDSN DLIRHFLIES SAKGVHLKGA DEEPYFGSLS AFVCQHSIMA LALPCKLTIP QRELGGADGA SDSTDSPASC QKKSAGCHTL YLSSVSVETL TGALAVQKAI STTFERDILP TPTVVHFKVT EQGITLTDVQ RKVFFRRHYP LTTLRFCGMD PEQRKWQKYC KPSWIFGFVA KSQTEPQENV CHLFAEYDMV QPASQVIGLV TALLQDAERM
TNS4 links the focal adhesion and cell adhesion signaling to the actin cytoskeleton. It may be involved in cell survival and migration. The protein may be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton and promote apoptosis, via its cleavage by caspase-3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C terminal tensin like; c-ten; C-terminal tensin-like protein; Tensin-4
Gene Aliases: CTEN; PP14434; TNS4
UniProt ID: (Human) Q8IZW8
Entrez Gene ID: (Human) 84951
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