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Application
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TOPBP1 Antibody (MA5-24436) in WB
Western blot analysis of TOPBP1 in Jurkat cells. Samples were probed using a Mouse Monoclonal TOPBP1 (6D12) Antibody (Product # MA5-24436).
Product Details
MA5-24436
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
6D12
Immunogen
TOPBP1 (NP_008958, 1327 a.a. ~ 1435 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2633408
Product Specific Information
Peptide Sequence: LLQSGGAKVL PGHSVPLFKE ATHLFSDLNK LKPDDSGVNI AEAAAQNVYC LRTEYIADYL MQESPPHVEN YCLPEAISFI QNNKELGTGL SQKRKAPTEK NKIKRPRVH
Target Information
This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DNA topoisomerase 2-binding protein 1; DNA topoisomerase II-beta-binding protein 1; DNA topoisomerase II-binding protein 1; TOPBP 1; TopBP1
Gene Aliases: KIAA0259; TOP2BP1; TOPBP1
UniProt ID: (Human) Q92547
Entrez Gene ID: (Human) 11073
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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