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Sequence of this protein is as follows: SNHFLYLPRD VLAQLPSLRH LDLSNNSLVS LTYVSFRNLT HLESLHLEDN ALKVLHNGTL AELQGLPHIR VFLDNNPWVC DCHMADMVTW LKETEVVQGK DRLTCAYPEK
This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. The encoded protein is an oncofetal antigen that is specific to trophoblast cells. In adults this protein is highly expressed in many tumor cells and is associated with poor clinical outcome in numerous cancers. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2009].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 5T4 oncofetal antigen; 5T4 oncofetal trophoblast glycoprotein; 5T4 oncotrophoblast glycoprotein; 5T4-AG; M6P1; Trophoblast glycoprotein; WAIF1; Wnt-activated inhibitory factor 1
Gene Aliases: 5T4; 5T4AG; M6P1; TPBG; WAIF1
UniProt ID: (Human) Q13641, (Rat) Q5PQV5
Entrez Gene ID: (Human) 7162, (Rat) 83684
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