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Product Details
13741-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TPM4 Fusion Protein Ag4679 (1-248 aa encoded by BC037576)
Conjugate
Unconjugated
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAGLNSLEA VKRKIQALQQ QADEAEDRAQ GLQRELDGER ERREKAEGDV AALNRRIQLV EEELDRAQER LATALQKLEE AEKAADESER GMKVIENRAM KDEEKMEIQE MQLKEAKHIA EEADRKYEEV ARKLVILEGE LERAEERAEV SELKCGDLEE ELKNVTNNLK SLEAASEKYS EKEDKYEEEI KLLSDKLKEA ETRAEFAERT VAKLEKTIDD LEEKLAQAKE ENVGLHQTLD QTLNELNCI (1-248 aa encoded by BC037576 )
Target Information
TPM4 (tropomyosin 4) is a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. TPM4 plays a central role in association with the troponin complex in the calcium dependent regulations of vertebrate striated muscle contraction. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: epididymis secretory protein Li 108; TM-4; TM30p1; tropomycin 4; tropomyosin; Tropomyosin alpha-4 chain; Tropomyosin-4
Gene Aliases: 2610528G24Rik; HEL-S-108; TPM4; Tpm4.2; Tpm4.2cy
UniProt ID: (Human) P67936, (Rat) P09495, (Mouse) Q6IRU2
Entrez Gene ID: (Human) 7171, (Rat) 24852, (Mouse) 326618
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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