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Bethyl Laboratories

TPR Polyclonal Antibody

View all (16) TPR antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (2)

Application

FIGURE: 1 / 2

TPR Antibody (A300-826A-T) in WB

Detection of human TPR by western blot. Samples: Whole cell lysate (50 µg) from HeLa, Jurkat, K-562, Hep-G2, and RKO cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-TPR antibody (Product # A300-826A) (lot A300-826A-2) used for WB at 0.04 µg/mL. Detection: Chemiluminescence with an exposure time of 3 seconds.

TPR Antibody in Immunoprecipitation (IP)

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Product Details

A300-826A-T

Applications

Tested Dilution

Publications

Western Blot (WB)

1:2,000-1:10,000

Immunoprecipitation (IP)

2-10 µg/mg lysate

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Region between residue 1650 and 1700 of Human Translocated Promoter Region Protein.

View immunogen

Conjugate

Unconjugated

Form

Liquid

Concentration

0.20 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

TBS, pH 7.0 to 8.0, with 0.1% BSA

Contains

0.09% sodium azide

Storage conditions

4°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

The recommended shelf life for this product is 1 year from date of receipt.

Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat

Target Information

Steroidogenic factor-1 (SF-1) regulates multiple genes involved in the adrenal and gonadal development and in the biosynthesis of a variety of hormones, including adrenal and gonadal steroids, anti-Mullerian hormone (AMH), and gonadotropins. SF-1 belongs to the fushi tarazu factor-1 (FTZ-F1) subfamily of orphan nuclear receptors. In the adult ovary, SF-1 localizes to theca/interstitial cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Megator; NPC-associated intranuclear protein; nuclear pore complex-associated protein TPR; Nucleoprotein TPR; translocated promoter region (to activated MET oncogene); Translocated promoter region protein; tumor potentiating region

Gene Aliases: TPR

UniProt ID: (Human) Q99968

Entrez Gene ID: (Human) 7175

Function(s)

molecular_function chromatin binding mRNA binding transporter activity nucleocytoplasmic transporter activity protein binding tubulin binding heat shock protein binding protein homodimerization activity protein anchor poly(A) RNA binding mitogen-activated protein kinase binding dynein complex binding primary active transporter

Process(es)

negative regulation of transcription from RNA polymerase II promoter MAPK import into nucleus RNA import into nucleus RNA export from nucleus mRNA export from nucleus tRNA export from nucleus protein import into nucleus protein export from nucleus nuclear pore organization mitotic nuclear division mitotic nuclear envelope disassembly mitotic spindle assembly checkpoint biological_process regulation of mRNA export from nucleus regulation of glucose transport regulation of mitotic sister chromatid separation viral process protein sumoylation viral transcription gene silencing by RNA positive regulation of heterochromatin assembly regulation of protein stability mRNA export from nucleus in response to heat stress cellular response to heat cellular response to interferon-alpha regulation of protein import into nucleus positive regulation of protein import into nucleus nuclear matrix organization negative regulation of translational initiation regulation of protein export from nucleus positive regulation of protein export from nucleus negative regulation of RNA export from nucleus nuclear pore complex assembly cell division response to epidermal growth factor intracellular transport of virus positive regulation of mitotic cell cycle spindle assembly checkpoint positive regulation of intracellular protein transport regulation of cellular response to heat regulation of mitotic spindle assembly

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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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