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Invitrogen
TRIF Polyclonal Antibody
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Application
FIGURE: 1 / 3
TRIF Antibody (PA5-23467) in IHC (P)
Immunohistochemical analysis of TRIF in formalin-fixed paraffin-embedded tissue section of mouse spleen. Samples were incubated in TRIF polyclonal antibody (Product # PA5-23467) using a dilution of 1:200 followed by HRP labeled anti-rabbit secondary antibody and DAB reagent. Nuclei of cells were counter-stained with hematoxylin.
Product Details
PA5-23467
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Pig,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide made to an internal portion of the mouse TRIF protein (between amino acids 100-180) [UniProt Q80UF7].
Conjugate
Unconjugated
Form
Liquid
Concentration
1.0 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2540967
Product Specific Information
Suggested positive control: antigen standard for TICAM1 (transient overexpression lysate), mouse spleen tissue or mouse spleen protein.
Target Information
Involved in innate immunity against invading pathogens. Adapter used by TLR3 and TLR4 (through TICAM2) to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: hCG_39321; HSD34; RNF36; TI; TICAM-1; TIR domain-containing adapter molecule 1; TIR domain-containing adapter protein inducing IFN-beta; TIR domain-containing adaptor inducing interferon-beta; TIR-domain containing adaptor inducing interferon-beta; toll-interleukin 1 receptor domain-containing adapter protein inducing interferon-beta; Toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta; toll-like receptor adaptor molecule 1
Gene Aliases: AW046014; AW547018; TICAM-1; Ticam1; TRIF
UniProt ID: (Mouse) Q80UF7
Entrez Gene ID: (Pig) 100623776, (Mouse) 106759, (Rat) 363328
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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