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Invitrogen

TRIM62 Polyclonal Antibody

View all (8) TRIM62 antibodies

Datasheet

Protocols

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Tech Support

Catalog # PA5-116643

Price (EUR)

498,00

100 µL

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Datasheet

Protocols

Questions & Answers

Tech Support

Antibody Testing Data (2)

Application

TRIM62 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 2

TRIM62 Antibody (PA5-116643) in IHC (P)

Immunohistochemistry analysis of TRIM62 in paraffin-embedded human colon. Samples were incubated with TRIM62 Polyclonal antibody (Product # PA5-116643) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.

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Product Details

PA5-116643

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

ELISA (ELISA)

1 µg/mL

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 120-280 of human TRIM62 (NP_0606772)

View immunogen

Conjugate

Unconjugated

Form

Liquid

Concentration

0.53 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_2901274

Product Specific Information

Positive Samples: A-431, Mouse brain

Immunogen sequence: HEQHQVTGID DAFDELQREL KDQLQALQDS EREHTEALQL LKRQLAETKS STKSLRTTIG EAFERLHRLL RERQKAMLEE LEADTARTLT DIEQKVQRYS QQLRKVQEGA QILQERLAET DRHTFLAGVA SLSERLKGKI HETNLTYEDF PTSKYTGPLQ Y

Target Information

E3 ubiquitin ligase whose activity is dependent on E2 ubiquitin-conjugating enzyme UBE2D2.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: ductal epithelium-associated RING Chromosome 1; E3 ubiquitin-protein ligase TRIM62; tripartite motif-containing 62; Tripartite motif-containing protein 62

Gene Aliases: 6330414G21Rik; AI450348; DEAR1; TRIM62

UniProt ID: (Human) Q9BVG3, (Mouse) Q80V85

Entrez Gene ID: (Human) 55223, (Rat) 313045, (Mouse) 67525

Function(s)

ubiquitin-protein transferase activity zinc ion binding ligase activity UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity ribosomal S6-glutamic acid ligase activity coenzyme F420-0 gamma-glutamyl ligase activity coenzyme F420-2 alpha-glutamyl ligase activity metal ion binding protein-glycine ligase activity protein-glycine ligase activity, initiating protein-glycine ligase activity, elongating tubulin-glycine ligase activity protein-glutamic acid ligase activity tubulin-glutamic acid ligase activity ubiquitin-protein ligase

Process(es)

negative regulation of epithelial to mesenchymal transition protein ubiquitination negative regulation of viral transcription positive regulation of I-kappaB kinase/NF-kappaB signaling innate immune response regulation of viral entry into host cell positive regulation of sequence-specific DNA binding transcription factor activity positive regulation of NF-kappaB transcription factor activity interferon-gamma-mediated signaling pathway regulation of viral release from host cell

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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