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Product Details
19602-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TRIP13 Fusion Protein Ag6595 (1-301 aa encoded by BC000404)
Conjugate
Form
Liquid
Concentration
0.37 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MDEAVGDLK QALPCVAESP TVHVEVHQRG SSTAKKEDIN LSVRKLLNRH NIVFGDYTWT EFDEPFLTRN VQSVSIIDTE LKVKDSQPID LSACTVALHI FQLNEDGPSS ENLEEETENI IAANHWVLPA AEFHGLWDSL VYDVEVKSHL LDYVMTTLLF SDKNVNSNLI TWNRVVLLHG PPGTGKTSLC KALAQKLTIR LSSRYRYGQL IEINSHSLFS KWFSESGKLV TKMFQKIQDL IDDKDALVFV LIDEVESLTA ARNACRAGTE PSDAIRVVNA VLTQIDQIKR HSNVVILTTS NI (1-301 aa encoded by BC000404)
Target Information
Thyroid hormone receptors (TRs) are transcription factors that regulate the expression of specific genes in a hormone-dependent manner. TRIP13 (thyroid hormone receptor interactor 13), also called 16E1BP, is a transcription factor that interacts with the ligand binding domain of the thyroid receptor (TR) as well as a variety of target genes including human papilloma virus type 16 (HPV16) E1. Unlike most TRIP proteins which function only in the presence of hormones, TRIP13 does not require the presence of thyroid hormone to interact with TR. The association of TRIP13 with (HPV16) E1 suggests that TRIP13 may have tumor suppressor gene function. TRIP13 is a 432 amino acid protein with 2 different isoforms produced by alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 16E1-BP; HPV16 E1 protein binding protein; HPV16 E1 protein-binding protein; Human papillomavirus type 16 E1 protein-binding protein; Pachytene checkpoint protein 2 homolog; Thyroid hormone receptor interactor 13; thyroid receptor interacting protein 13; Thyroid receptor-interacting protein 13; TR-interacting protein 13; TRIP-13
Gene Aliases: 16E1BP; 2410002G23Rik; D13Ertd328e; PCH2; TRIP13
UniProt ID: (Human) Q15645, (Rat) Q5XHZ9, (Mouse) Q3UA06
Entrez Gene ID: (Human) 9319, (Rat) 292206, (Mouse) 69716
oocyte maturation
double-strand break repair
transcription from RNA polymerase II promoter
synaptonemal complex assembly
reciprocal meiotic recombination
male meiosis I
female meiosis I
spermatogenesis
spermatid development
oogenesis
regulation of nucleic acid-templated transcription
cell differentiation
meiotic cell cycle
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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