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Product Details
12324-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Rat,
Human,
Mouse
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TRIP4 Fusion Protein Ag2987 (282-581 aa encoded by BC012448)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: VIDDESDYF ASDSNQWLSK LERETLQKRE EELRELRHAS RLSKKVTIDF AGRKILEEEN SLAEYHSRLD ETIQAIANGT LNQPLTKLDR SSEEPLGVLV NPNMYQSPPQ WVDHTGAASQ KKAFRSSGFG LEFNSFQHQL RIQDQEFQEG FDGGWCLSVH QPWASLLVRG IKRVEGRSWY TPHRGRLWIA ATAKKPSPQE VSELQATYRL LRGKDVEFPN DYPSGCLLGC VDLIDCLSQK QFKEQFPDIS QESDSPFVFI CKNPQEMVVK FPIKGNPKIW KLDSKIHQGA KKGLMKQNKA V (282-581 aa encoded by BC012448)
Target Information
Transcription coactivator of nuclear receptors which functions in conjunction with CBP-p300 and SRC-1 and may play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1. Acts as a mediator of transrepression between nuclear receptor and either AP1 or NF-kappa-B. Plays a role in androgen receptor transactivation and in testicular function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Activating signal cointegrator 1; ASC-1; Thyroid receptor-interacting protein 4; TR-interacting protein 4; transcription coactivator Asc1; TRIP-4; zinc finger, C2HC5-type
Gene Aliases: 4930558E03Rik; ASC-1; ASC1; BB191711; HsT17391; RQT4; SMABF1; TRIP4; ZC2HC5
UniProt ID: (Human) Q15650, (Mouse) Q9QXN3
Entrez Gene ID: (Human) 9325, (Rat) 315769, (Mouse) 56404
protease binding
transcription coactivator activity
protein binding
zinc ion binding
ligand-dependent nuclear receptor binding
estrogen receptor binding
histone acetyltransferase binding
ubiquitin-like protein ligase binding
metal ion binding
transcription cofactor
gene-specific transcriptional regulator
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