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Product Details
PA5-54330
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human TRP1. Recombinant protein control fragment (Product #RP-91251).
Conjugate
Unconjugated
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2648976
Product Specific Information
Immunogen sequence: HEDKEWKFAR AKLWLSYFDD KCTLPPPFNI IPSPKTICYM ISSLSKWICS HTSKGKVKRQ NSLKEWRNLK QKRDENYQKV MCCLVHRYLT SMRQKMQSTD QATVENLNEL RQDLSKFRNE IRDLLGFRTS KYA
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 98%.
Target Information
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion. Interacts with ITPR3. Appears to be ubiquitous.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: capacitative calcium channel protein Trp1; Short transient receptor potential channel 1; transient receptor potential canonical 1; transient receptor potential cation channel, subfamily C, member 1; Transient receptor protein 1; TRP-1; TrpC1
Gene Aliases: HTRP-1; TRP1; TRPC1
UniProt ID: (Human) P48995
Entrez Gene ID: (Human) 7220
calcium ion transport
manganese ion transport
melanin biosynthetic process
positive regulation of release of sequestered calcium ion into cytosol
regulation of cytosolic calcium ion concentration
response to calcium ion
calcium ion transmembrane transport
cellular response to hypoxia
regulation of cardiac conduction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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