Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: TRPM2.
TRPM2 belongs to the ion transport protein family which includes Sodium, Potassium, Calcium ion channels. This family is characterized by proteins possessing 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. TRPM2 is activated by oxidative stress and confers susceptibility to cell death. Further, TRPM2 is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. Several alternatively spliced transcript variants of the TRPM2 gene have been described, but their full-length nature is not known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: EC 3.6.1.13; EREG 1; KNP 3; LTRPC 2; MGC133383; null; Transient receptor potential cation channel subfamily M member 2; transient receptor potential melastatin family 2; TRPC 7; TRPM 2
Gene Aliases: Trpm2; Trpm2-predicted
UniProt ID: (Rat) E9PTA2
Entrez Gene ID: (Rat) 294329
Molecular Function:
ion channel
transporter
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