Search Thermo Fisher Scientific
- Order Status
- Quick Order
-
Don't have an account ? Create Account
Search Thermo Fisher Scientific
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
TRPM2 belongs to the ion transport protein family which includes Sodium, Potassium, Calcium ion channels. This family is characterized by proteins possessing 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. TRPM2 is activated by oxidative stress and confers susceptibility to cell death. Further, TRPM2 is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. Several alternatively spliced transcript variants of the TRPM2 gene have been described, but their full-length nature is not known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: EC 3.6.1.13; EREG 1; Estrogen-responsive element-associated gene 1 protein; KNP 3; Long transient receptor potential channel 2; LTRPC 2; LTrpC-2; MGC133383; Transient receptor potential cation channel subfamily M member 2; transient receptor potential cation channel, subfamily M, member 2; Transient receptor potential channel 7; Transient receptor potential melastatin 2; TRPC 7; TrpC7; TRPM 2
Gene Aliases: EREG1; KNP3; LTrpC-2; LTRPC2; NUDT9H; NUDT9L1; TRPC7; TRPM2
UniProt ID: (Human) O94759
Entrez Gene ID: (Human) 7226
Molecular Function:
hydrolase
ion channel
transporter
metabolite interconversion enzyme
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support