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            • Primary Antibodies ›
            • TRPS1 Antibodies

            OriGene

            TRPS1 Monoclonal Antibody (OTI8C11)

            View all (29) TRPS1 antibodies
            Datasheet
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            Catalog # CF813180
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            Price (USD)
            662.00
            100 µg
             
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            Cite TRPS1 Monoclonal Antibody (OTI8C11)

            • Antibody Testing Data (1)
            Application
            TRPS1 Antibody in Western Blot (WB)
            Group 53 Created with Sketch.

            FIGURE: 1 / 1

            TRPS1 Antibody (CF813180) in WB

            HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TRPS1 (RC215856, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TRPS1 (1:500).
            View Product

            TRPS1 Antibody in Western Blot (WB)

            Product Details

            CF813180

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            1:500
            -
            Product Specifications

            Species Reactivity

            Human, Mouse, Rat

            Host/Isotype

            Mouse / IgG2b

            Class

            Monoclonal

            Type

            Antibody

            Clone

            OTI8C11

            Immunogen

            Human recombinant protein fragment corresponding to amino acids 985-1281 of human TRPS1 (NP_054831) produced in E.coli.
            View immunogen

            Conjugate

            Unconjugated

            Form

            Lyophilized

            Concentration

            1 mg/mL

            Purification

            Affinity chromatography

            Storage buffer

            PBS with 8% trehalose

            Contains

            no preservative

            Storage conditions

            -20°C

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            Product Specific Information

            For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)

            Target Information

            This gene encodes a transcription factor that represses GATA-regulated genes and binds to a dynein light chain protein. Binding of the encoded protein to the dynein light chain protein affects binding to GATA consensus sequences and suppresses its transcriptional activity. Defects in this gene are a cause of tricho-rhino-phalangeal syndrome (TRPS) types I-III. [provided by RefSeq].

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            References (0)

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            Cite this product

            Bioinformatics

            Protein Aliases: Tricho-rhino-phalangeal syndrome type I protein; trichorhinophalangeal syndrome I; trichorhinophalangeal syndrome I homolog; Zinc finger protein GC79; Zinc finger transcription factor Trps1

            View more View less

            Gene Aliases: AI115454; AI447310; D15Ertd586e; GC79; LGCR; TRPS1

            View more View less

            UniProt ID: (Human) Q9UHF7

            View more View less

            Entrez Gene ID: (Human) 7227, (Mouse) 83925, (Rat) 299897

            View more View less

            Function(s)

            RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II transcription factor binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding chromatin binding transcription factor activity, sequence-specific DNA binding protein binding zinc ion binding DNA binding sequence-specific DNA binding metal ion binding molecular_function DNA-binding transcription factor gene-specific transcriptional regulator C2H2 zinc finger transcription factor

            Process(es)

            negative regulation of transcription from RNA polymerase II promoter skeletal system development transcription from RNA polymerase II promoter NLS-bearing protein import into nucleus heart development organ morphogenesis tissue development regulation of chondrocyte differentiation cell fate commitment positive regulation of transcription from RNA polymerase II promoter cell development digestive tract development anatomical structure formation involved in morphogenesis chondrocyte differentiation transcription, DNA-templated regulation of transcription, DNA-templated transmembrane receptor protein serine/threonine kinase signaling pathway regulation of histone deacetylation negative regulation of transcription, DNA-templated positive regulation of extrinsic apoptotic signaling pathway via death domain receptors biological_process
            It has to be done as per old AB suggested Products section.
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            Performance Guarantee

            If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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