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OriGene
TSC22 domain family, member 4 (TSC22D4) Monoclonal Antibody (OTI3G6), TrueMAB™
Product Details
CF811733
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI3G6
Immunogen
Human recombinant protein fragment corresponding to amino acids 1-395 of human TSC22D4 (NP_112197) produced in E.coli.
Conjugate
Unconjugated
Form
Lyophilized
Concentration
See Label
Purification
Protein A/G
Storage buffer
PBS, pH 7.3, with 8% trehalose
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
TSC22D4 is a member of the TSC22 domain family of leucine zipper transcriptional regulators. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity. An important paralog of this gene is TSC22D1.
Binds DNA and acts as a transcriptional repressor (PubMed:10488076). Involved in the regulation of systematic glucose homeostasis and insulin sensitivity, via transcriptional repression of downstream insulin signaling targets such as OBP2A/LCN13 (By similarity). Acts as a negative regulator of lipogenic gene expression in hepatocytes and thereby mediates the control of very low-density lipoprotein release (PubMed:23307490). May play a role in neurite elongation and survival (By similarity).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: tsc-22-like protein THG-1; TSC22 domain family 4; TSC22 domain family protein 4; TSC22 domain family, member 4; TSC22-related inducible leucine zipper 2; TSC22-related-inducible leucine zipper protein 2
Gene Aliases: 0610009M14Rik; 1700023B23Rik; AI415410; THG-1; Thg-1pit; THG1; THG1-PIT; TILZ2; TSC22D4
UniProt ID: (Human) Q9Y3Q8, (Mouse) Q9EQN3, (Rat) Q3B8N7
Entrez Gene ID: (Human) 81628, (Mouse) 78829, (Rat) 684980
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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