Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
20320-1-AP
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TSPAN32 Fusion Protein Ag14174 (100-202 aa encoded by BC016693)
Conjugate
Form
Liquid
Concentration
0.19 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: LAFCAQVQV VFWRLHSPTQ VEDAMLDTYD LVYEQAMKGT SHVRRQELAA IQDVFLCCGK KSPFSRLGST EADLCQGEEA AREDCLQGIR SFLRTHQQVA SSLT (100-202 aa encoded by B C016693)
Target Information
This gene, which is a member of the tetraspanin superfamily, is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. This gene is located among several imprinted genes; however, this gene, as well as the tumor-suppressing subchromosomal transferable fragment 4, escapes imprinting. This gene may play a role in malignancies and diseases that involve this region, and it is also involved in hematopoietic cell function. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: AML1-regulated transmembrane protein 1; FLJ17158; FLJ97586; MGC22455; pan hematopoietic expression; pan-hematopoietic expression protein; Protein Phemx; tetraspanin; Tetraspanin-32; Tspan-32; tumor-suppressing STF cDNA 6; tumor-suppressing subchromosomal transferable fragment 6; tumor-suppressing subchromosomal transferable fragment cDNA 6; tumor-suppressing subtransferable candidate 6
Gene Aliases: Art-1; ART1; AW208513; BB235973; D7Wsu37e; PHEMX; PHMX; TSPAN32; TSSC6
UniProt ID: (Human) Q96QS1, (Mouse) Q9JHH2
Entrez Gene ID: (Human) 10077, (Mouse) 27027
cytoskeleton organization
integrin-mediated signaling pathway
blood coagulation
hemostasis
negative regulation of cell proliferation
negative regulation of myeloid dendritic cell activation
defense response to protozoan
regulation of defense response to virus
platelet aggregation
cell surface receptor signaling pathway
cell-cell signaling
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support