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Involved in modulation of cell growth and cellular response to gamma radiation probably via regulation of the Akt signaling pathway. Involved in regulation of p53/TP53. Suppresses p53/TP53 protein levels and promotes its ubiquitination; the function is dependent on USP7 and independent on MDM2. Proposed to displace p53/TP53 from interaction with USP7.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: testis-specific protein, Y-encoded-like 5; Testis-specific Y-encoded-like protein 5; TSPY-like 5; TSPY-like protein 5
Gene Aliases: 6330530B20; E130308C19Rik; KIAA1750; TSPYL5
UniProt ID: (Human) Q86VY4, (Mouse) Q69ZB3
Entrez Gene ID: (Human) 85453, (Rat) 314555, (Mouse) 239364
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