Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
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Immunogen sequence: SQEKEVLSYL NSLEVEELGL ARLGYKIKFY FDRNPYFQNK VLIKEYGCGP SGQVVSRSTP IQWLPGHDLQ SLSQGNPENN RSFFGWFSNH SSIESDKIVE IINEELWPNP LQFYLLSEGA RV
Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 88%.
Involved in modulation of cell growth and cellular response to gamma radiation probably via regulation of the Akt signaling pathway. Involved in regulation of p53/TP53. Suppresses p53/TP53 protein levels and promotes its ubiquitination; the function is dependent on USP7 and independent on MDM2. Proposed to displace p53/TP53 from interaction with USP7.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Testis-specific Y-encoded-like protein 5; TSPY-like 5; TSPY-like protein 5
Gene Aliases: KIAA1750; TSPYL5
UniProt ID: (Human) Q86VY4
Entrez Gene ID: (Human) 85453
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