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Application
FIGURE: 1 / 3
Thromboxane A2 Receptor Antibody (APR-069-200UL) in IHC (F)
Expression of thromboxane A2 receptor in mouse cortex and hippocampus - Immunohistochemical staining of perfusion-fixed frozen mouse brain sections with Anti-Thromboxane A2 Receptor Antibody (#APR-069), (1:200), followed by goat Anti-rabbit-AlexaFluor-488. A. TBXA2R immunoreactivity (green) is observed in mouse parietal cortex neurons (arrows). B. TBXA2R immunoreactivity (green) is detected in neurons (hori... View More
Product Details
APR-069-200UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)HAREATQRPRD(S)EVE, corresponding to amino acid residues 225-239 of rat TBXA2R, 3rd intracellular loop
Conjugate
Unconjugated
Form
Lyophilized
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
The thromboxane A2 receptor (TBXA2R) is a member of the Prostanoid Receptor subfamily. TBXA2R performs an essential role in hemostasis by interacting with thromboxane A2 to induce platelet aggregation. Thromboxane A2 has been implicated in myocardial infarct, stroke, and asthma. Additionally, thromboxane-prostanoid receptors have been implicated in the pathogenesis of cardiovascular diseases. Changes in TBXA2R function have also been linked to a hereditary bleeding disorder.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Prostanoid TP receptor; Thromboxane A2 receptor; thromboxane prostanoid; Thromboxane receptor; TXA2 receptor; TXA2-R; TXR2
Gene Aliases: BDPLT13; TBXA2R; TP; TXA2-R
UniProt ID: (Human) P21731, (Mouse) P30987, (Rat) P34978
Entrez Gene ID: (Human) 6915, (Mouse) 21390, (Rat) 24816
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