Product References
Antiaging gene Klotho regulates epithelial-mesenchymal transition and increases sensitivity to pemetrexed by inducing lipocalin-2 expression.
Oncology letters
Takegahara K,Usuda J,Inoue T,Sonokawa T,Matsui T,Matsumoto M
35-5800 was used in Western Blot to hypothesize that the Klotho gene is involved in the metastatic/invasive ability of lung cancer.
Sat May 01 00:00:00 EDT 2021
Antiaging gene Klotho regulates epithelial-mesenchymal transition and increases sensitivity to pemetrexed by inducing lipocalin-2 expression.
Oncology letters
Takegahara K,Usuda J,Inoue T,Sonokawa T,Matsui T,Matsumoto M
35-5800 was used in Western Blot to hypothesize that the Klotho gene is involved in the metastatic/invasive ability of lung cancer.
Sat May 01 00:00:00 EDT 2021
Impact of intratumoral expression levels of fluoropyrimidine-metabolizing enzymes on treatment outcomes of adjuvant S-1 therapy in gastric cancer.
PloS one
Kim JY,Shin E,Kim JW,Lee HS,Lee DW,Kim SH,Lee JO,Kim YJ,Kim JH,Bang SM,Ahn SH,Park DJ,Lee JS,Lee JS,Kim HH,Lee KW
35-5800 was used in immunohistochemistry - paraffin section to identify biomarkers relevant to treatment outcomes in gastric cancer patients receiving adjuvant S-1 chemotherapy.
Tue Feb 09 00:00:00 EST 2016
Molecular profiling in gastric cancer: examining potential targets for chemotherapy.
Journal of surgical oncology
Miura JT,Johnston FM,Thomas J,George B,Eastwood D,Tsai S,Christians KK,Turaga KK,Gamblin TC
35-5800 was used in immunohistochemistry (paraffin) to use molecular profiling to assess expression of biomarkers of operable gastric adenocarcinoma being treated with epirubicin, cisplatin, and 5-fluorouracil.
Mon Sep 01 00:00:00 EDT 2014
The poison oligonucleotide F10 is highly effective against acute lymphoblastic leukemia while sparing normal hematopoietic cells.
Oncotarget
Pardee TS,Stadelman K,Jennings-Gee J,Caudell DL,Gmeiner WH
35-5800 was used in western blot to evaluate the therapeutic potential of oligonucleotide F10 against against acute lymphoblastic leukemia
Mon Jun 30 00:00:00 EDT 2014
Thymidylate synthase and folyl-polyglutamate synthase are not clinically useful markers of response to pemetrexed in patients with malignant pleural mesothelioma.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
Lustgarten DE,Deshpande C,Aggarwal C,Wang LC,Saloura V,Vachani A,Wang LP,Litzky L,Feldman M,Creaney J,Nowak AK,Langer C,Inghilleri S,Stella G,Albelda SM
35-5800 was used in immunohistochemistry to examine the use of thymidylate synthase and folylpolyglutamate synthase as biomarkers to predict the of outcome after pemetrexed in patients.
Mon Apr 01 00:00:00 EDT 2013
Translational repression of thymidylate synthase by targeting its mRNA.
Nucleic acids research
Garg D,Beribisky AV,Ponterini G,Ligabue A,Marverti G,Martello A,Costi MP,Sattler M,Wade RC
35-5800 was used in western blot to elucidate how Hoechst 33258 reduces thymidylate synthase
Mon Apr 01 00:00:00 EDT 2013
Unique dual targeting of thymidylate synthase and topoisomerase1 by FdUMP[10] results in high efficacy against AML and low toxicity.
Blood
Pardee TS,Gomes E,Jennings-Gee J,Caudell D,Gmeiner WH
35-5800 was used in western blot to characterize the anti-cancer properties of fluoropyrimidine.
Thu Apr 12 00:00:00 EDT 2012
Unique dual targeting of thymidylate synthase and topoisomerase1 by FdUMP[10] results in high efficacy against AML and low toxicity.
Blood
Pardee TS,Gomes E,Jennings-Gee J,Caudell D,Gmeiner WH
35-5800 was used in western blot to characterize the anti-cancer properties of fluoropyrimidine.
Thu Apr 12 00:00:00 EDT 2012
Phase 2 trial of oxaliplatin and pemetrexed as an induction regimen in locally advanced head and neck cancer.
Cancer
Gilbert J,Murphy B,Dietrich MS,Henry E,Jordan R,Counsell A,Wirth P,Yarbrough WG,Slebos RJ,Chung CH
35-5800 was used in immunohistochemistry to report the results of a phase II trail to evaluate the tolerability and clinical efficacy of using oxaliplatin and pemetrexed to treat locally advanced head and neck squamous cell carcinoma.
Wed Feb 15 00:00:00 EST 2012
Biological evaluation of MR36, a novel non-polyglutamatable thymidylate synthase inhibitor that blocks cell cycle progression in melanoma cell lines.
Investigational new drugs
Giudice S,Benassi L,Bertazzoni G,Veratti E,Morini D,Azzoni P,Costi MP,Venturelli A,Pirondi S,Seidenari S,Magnoni C
35-5800 was used in western blot to investigate the relationship between folate and apoptosis using melanoma cells.
Wed Aug 01 00:00:00 EDT 2012
Thymidylate synthase and thymidine phosphorylase as predictive markers of capecitabine monotherapy in patients with anthracycline- and taxane-pretreated metastatic breast cancer.
Cancer chemotherapy and pharmacology
Lee SJ,Choi YL,Park YH,Kim ST,Cho EY,Ahn JS,Im YH
355800 was used in immunohistochemistry - paraffin section to assess the use of thymidylate synthase and thymidine phosphorylase as biomarkers to predict clinical outcomes of capecitabine monotherapy in patients with anthracycline- and taxane-pretreated metastatic breast cancer
Thu Sep 01 00:00:00 EDT 2011
Thymidylate synthase but not excision repair cross-complementation group 1 tumor expression predicts outcome in patients with malignant pleural mesothelioma treated with pemetrexed-based chemotherapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Righi L,Papotti MG,Ceppi P,Billè A,Bacillo E,Molinaro L,Ruffini E,Scagliotti GV,Selvaggi G
35-5800 was used in immunohistochemistry - paraffin section to investigate the prognostic effectiveness of thymidylate synthase in the chemotherapy of malignant pleural mesothelioma
Sat Mar 20 00:00:00 EDT 2010
Thymidine synthase, thymidine phosphorylase, and excision repair cross-complementation group 1 expression as predictive markers of capecitabine plus cisplatin chemotherapy as first-line treatment for patients with advanced oesophageal squamous cell carcinoma.
British journal of cancer
Lee S,Park YH,Kim KH,Cho EY,Ahn YC,Kim K,Shim YM,Ahn JS,Park K,Im YH
355800 was used in immunohistochemistry - paraffin section to study biomarkers for predicting the response to capecitabine and cisplatin combination chemotherapy in metastatic oesophageal squamous cell cancer
Tue Sep 07 00:00:00 EDT 2010
Expression of thymidylate synthase determines the response of gastric cancer patients undergoing gastrectomy to 5-fluorouracil-based adjuvant chemotherapy.
Langenbeck's archives of surgery
Yeh CN,Jung SM,Chen TW,Hwang TL,Jan YY,Chen MF
Mon Mar 01 00:00:00 EST 2010
beta-Tubulin-II expression strongly predicts outcome in patients receiving induction chemotherapy for locally advanced squamous carcinoma of the head and neck: a companion analysis of the TAX 324 trial.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Cullen KJ,Schumaker L,Nikitakis N,Goloubeva O,Tan M,Sarlis NJ,Haddad RI,Posner MR
Sun Dec 20 00:00:00 EST 2009
beta-Tubulin-II expression strongly predicts outcome in patients receiving induction chemotherapy for locally advanced squamous carcinoma of the head and neck: a companion analysis of the TAX 324 trial.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Cullen KJ,Schumaker L,Nikitakis N,Goloubeva O,Tan M,Sarlis NJ,Haddad RI,Posner MR
Sun Dec 20 00:00:00 EST 2009
Adjuvant chemotherapy in completely resected gastric cancer: a randomized phase III trial conducted by GOIRC.
Journal of the National Cancer Institute
Di Costanzo F,Gasperoni S,Manzione L,Bisagni G,Labianca R,Bravi S,Cortesi E,Carlini P,Bracci R,Tomao S,Messerini L,Arcangeli A,Torri V,Bilancia D,Floriani I,Tonato M,Dinota A,Strafiuso G,Corgna E,Porrozzi S,Boni C,Rondini E,Giunta A,Monzio Compagnoni B,Biagioni F,Cesari M,Fornarini G,Nelli F,Carboni M,Cognetti F,Enzo MR,Piga A,Romiti A,Olivetti A,Masoni L,De Stefanis M,Dalla Mola A,Camera S,Recchia F,De Filippis S,Scipioni L,Zironi S,Luppi G,Italia M,Banducci S,Pisani Leretti A,Massidda B,Ionta MT,Nicolosi A,Canaletti R,Biscottini B,Grigniani F,Di Costanzo F,Rovei R,Croce E,Carroccio R,Gilli G,Cavalli C,Olgiati A,Pandolfi U,Rossetti R,Natalini G,Foa P,Oldani S,Bruno L,Cascinu S,Catalano G,Catalano V,Lungarotti F,Farris A,Sarobba MG,Trignano M,Muscogiuri A,Francavilla F,Figoli F,Leoni M,Papiani G,Orselli G,Antimi M,Bellini V,Cabassi A,Contu A,Pazzola A,Frignano M,Lastraioli E,Saggese M,Bianchini D,Antonuzzo L,Mela M,Camisa R
35-5800 was used in immunohistochemistry - paraffin section to discuss the results and consequences of surgical resection of gastric cancer
Wed Mar 19 00:00:00 EDT 2008
ERCC1 predicting chemoradiation resistance and poor outcome in oesophageal cancer.
European journal of cancer (Oxford, England : 1990)
Kim MK,Cho KJ,Kwon GY,Park SI,Kim YH,Kim JH,Song HY,Shin JH,Jung HY,Lee GH,Choi KD,Kim SB
35-5800 was used in immunohistochemistry - paraffin section to study the value of ERCC1 expression in predicting chemoradiation resistance and poor outcome in oesophageal cancer
Tue Jan 01 00:00:00 EST 2008
Thymidylate synthase and microsatellite instability in colorectal cancer: implications for disease free survival, treatment response and survival with metastases.
Acta oncologica (Stockholm, Sweden)
Bendardaf R,Lamlum H,Ristamäki R,Korkeila E,Syrjänen K,Pyrhönen S
35-5800 was used in immunohistochemistry - paraffin section to evaluate thymidylate synthase and microsatellite instability in colorectal cancer
Mon Nov 17 00:00:00 EST 2008
High thymidylate synthase expression in colorectal cancer with microsatellite instability: implications for chemotherapeutic strategies.
Clinical cancer research : an official journal of the American Association for Cancer Research
Ricciardiello L,Ceccarelli C,Angiolini G,Pariali M,Chieco P,Paterini P,Biasco G,Martinelli GN,Roda E,Bazzoli F
35-5800 was used in immunohistochemistry - paraffin section to study the role of high thymidylate synthase expression in colorectal cancer with microsatellite instability
Wed Jun 01 00:00:00 EDT 2005
The role of cAMP-dependent signaling in receptor-recognized forms of alpha 2-macroglobulin-induced cellular proliferation.
The Journal of biological chemistry
Misra UK,Akabani G,Pizzo SV
Fri Sep 27 00:00:00 EDT 2002