Loading ...

GenScript

Trx-tag Monoclonal Antibody (4C12H10)

Name: Trx-tag Monoclonal Antibody (4C12H10)
Brand: GenScript
SKU: A0018040
Price: 132.0 USD

2 References

View all (4) TRX-Tag antibodies

Datasheet

Protocols

Questions & Answers

Catalog # A00180-40

Price (USD)

132.00

40 µg

Estimated availability date: 17-Jun-2025

Check your price

Request bulk or custom format

Join Aspire^™ for free antibodies

Datasheet

Protocols

Questions & Answers

Product Details

A00180-40

Applications

Tested Dilution

Publications

Western Blot (WB)

0.3-1.0 µg/mL

ELISA (ELISA)

0.1-1.0 µg/mL

Miscellaneous PubMed (Misc)

View 2 publications 2 publications

Product Specifications

Species Reactivity

Bacteria, Human

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

4C12H10

Immunogen

Purified recombinant Trx-tag fusion protein

Conjugate

Unconjugated

Form

Lyophilized

Purification

Protein A

Storage buffer

PBS

Contains

0.02% sodium azide

Storage conditions

-20°C or -80°C if preferred

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Reconstitute the lyophilized antibody with deionized water (or equivalent) to a final concentration of 0.5 mg/ml.

Mouse Anti-Trx-tag Monoclonal Antibody reacts with the 109-aa Trx-tag sequence encoded by the PET-32a expression vectors from Novagen. Mouse Anti-Trx-tag Monoclonal Antibody is suitable for detecting fusion proteins that contain a Trx-tag.

Target Information

The TRX fusion tag is derived from thioredoxin reductase. Thioredoxin reductase interacts with glutaredoxin and glutathione reductase and catalyzes disulfide bond isomerization.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

The RBG-1-RBG-2 complex modulates autophagy activity by regulating lysosomal biogenesis and function in C. elegans.

Journal of cell science

Wang Z,Zhao H,Yuan C,Zhao D,Sun Y,Wang X,Zhang H

Vici syndrome is a severe and progressive multisystem disease caused by mutations in the gene. In patient tissues and animal models loss of function is associated with defective autophagy caused by accumulation of non-degradative autolysosomes but very little is known about the mechanism underlying this cellular phenotype. Here we demonstrate that loss of function of the RBG-1-RBG-2 complex ameliorates the autophagy defect in mutants. The suppression effect is independent of the complex's act

Tue Oct 01 00:00:00 UTC 2019

Immunization of Pigs by DNA Prime and Recombinant Vaccinia Virus Boost To Identify and Rank African Swine Fever Virus Immunogenic and Protective Proteins.

Journal of virology

Jancovich JK,Chapman D,Hansen DT,Robida MD,Loskutov A,Craciunescu F,Borovkov A,Kibler K,Goatley L,King K,Netherton CL,Taylor G,Jacobs B,Sykes K,Dixon LK

African swine fever virus (ASFV) causes an acute hemorrhagic fever in domestic pigs with high socioeconomic impact. No vaccine is available limiting options for control. Although live attenuated ASFV can induce up to 100% protection against lethal challenge little is known of the antigens which induce this protective response. To identify additional ASFV immunogenic and potentially protective antigens we cloned 47 viral genes in individual plasmids for gene vaccination and in recombinant vaccini

Sun Apr 15 00:00:00 UTC 2018

Bioinformatics

Protein Aliases: thioredoxin; Thioredoxin and glutathione reductase; thioredoxin glutathione reductase; thioredoxin reductase 2; Thioredoxin reductase 3; Thioredoxin reductase 3 intronic transcript 1; Thioredoxin reductase 3 neighbor gene; Thioredoxin reductase TR2; TXNRD3

Gene Aliases: TGR; TR2; TRXR3; TXNRD3; TXNRD3IT1; TXNRD3NB

UniProt ID: (Human) Q86VQ6

Entrez Gene ID: (Human) 114112

Function(s)

thioredoxin-disulfide reductase activity electron carrier activity protein disulfide oxidoreductase activity flavin adenine dinucleotide binding reductase

Process(es)

multicellular organism development spermatogenesis cell differentiation cell redox homeostasis oxidation-reduction process cellular oxidant detoxification

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more