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Invitrogen
UBE2A/UBE2B Polyclonal Antibody
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Application
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UBE2A/UBE2B Antibody (PA5-104442) in IHC (P)
Immunohistochemistry analysis of UBE2A/UBE2B in rat testis tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with UBE2A/UBE2B polyclonal antibody (Product # PA5-104442) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-104442
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human UBE2B(Accession P63146), corresponding to amino acid residues N94-I144.
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2816021
Product Specific Information
Antibody detects endogenous levels of total UBE2A/B.
Target Information
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E2 protein; E2 ubiquitin-conjugating enzyme A; E2 ubiquitin-conjugating enzyme B; E2(14k); E214K; HR6A; HR6B; RAD6 homolog A; RAD6 homolog B; Ubiquitin carrier protein A; Ubiquitin carrier protein B; ubiquitin conjugating enzyme; ubiquitin conjugating enzyme E2A; ubiquitin conjugating enzyme E2B; Ubiquitin-conjugating enzyme E2 A; Ubiquitin-conjugating enzyme E2 B; Ubiquitin-conjugating enzyme E2(14k); Ubiquitin-conjugating enzyme E2-17 kDa; ubiquitin-conjugating enzyme E2A (RAD6 homolog); ubiquitin-conjugating enzyme E2A, RAD6 homolog; ubiquitin-conjugating enzyme E2B (RAD6 homolog); ubiquitin-conjugating enzyme E2B (RAD6 homolog, S. cerevisiae); ubiquitin-conjugating enzyme E2B, RAD6 homolog; ubiquitin-conjugating enzyme E2B, RAD6 homology; ubiquitin-conjugating enzyme HR6A; Ubiquitin-protein ligase A; Ubiquitin-protein ligase B
Gene Aliases: 2610301N02Rik; E2-14k; E2-17kDa; HHR6A; HHR6B; HR6A; HR6B; Mhr6a; mHR6B; MRXS30; MRXSN; RAD6A; RAD6B; UBC2; UBCH1; UBE2A; UBE2B
UniProt ID: (Human) P49459, (Human) P63146, (Mouse) Q9Z255, (Rat) P63149, (Mouse) P63147
Entrez Gene ID: (Human) 7319, (Human) 7320, (Rat) 298317, (Mouse) 22209, (Rat) 81816, (Mouse) 22210
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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