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Invitrogen
UBE2L6 Recombinant Rabbit Monoclonal Antibody (6H8L5)
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Application
FIGURE: 1 / 5
UBE2L6 Antibody (703136) in ICC/IF
For immunofluorescence analysis, THP-1 cells were fixed and permeabilized for detection of endogenous UBE2L6 using Anti-UBE2L6 Recombinant Rabbit Monoclonal Antibody (Product # 703136, 1:500) and labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034, 1:2000). Nuclei (blue) were stained using ProLong™ Diamond Antifade Mountant with DAPI (Product # P36962) and cytoskeletal F-actin (red) staining using Rhodamine Phalloidin (Product # R415, 1:300) Panel a-d) shows represen... View More
Product Details
703136
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
Expi293
Class
Recombinant Monoclonal
Type
Antibody
Clone
6H8L5
Immunogen
Protein corresponding to human UBE2L6 [aa1-aa137]
Conjugate
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2784564
Product Specific Information
This antibody is predicted to react with Monkey, Pig, Mouse, Horse.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L6 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to function in the E6/E6-ap-induced ubiquitination of p53.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E2 ubiquitin-conjugating enzyme L6; MGC40331; retinoic acid induced gene B protein; Retinoic acid-induced gene B protein; RIG-B; UbcH8; Ubiquitin carrier protein L6; ubiquitin conjugating enzyme E2L 6; ubiquitin-conjugating enzyme E2L 6; Ubiquitin-protein ligase L6; Ubiquitin/ISG15-conjugating enzyme E2 L6
Gene Aliases: RIG-B; UBCH8; UBE2L6
UniProt ID: (Human) O14933
Entrez Gene ID: (Human) 9246
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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