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Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Mouse, Rat, Dog, Elephant, Opossum, Turkey, Chicken, Lizard (100%); Orangutan, Monkey, Bovine, Horse, Rabbit, Pig, Salmon (94%); Pufferfish, Zebrafish, Stickleback, Water flea (89%); Xenopus (83%).
For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Regulatory associated protein of mTOR (RAPTOR) is a binding partner of target of rapamycin (TOR). It binds to 4EBP1 and p70alpha. The binding of raptor to mTOR is essential for the mTOR-catalyzed phosphorylation of 4EBP1 in vitro. It enhances the mTOR kinase activity toward p70alpha. It is also an essential scaffold for the mTOR-catalyzed phosphorylation of 4EBP1 and mediates TOR action in vivo.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: testicular tissue protein Li 221; ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase); Ubiquitin carboxyl-terminal hydrolase isozyme L3; ubiquitin carboxyl-terminal hydrolase-6; Ubiquitin thioesterase L3; ubiquitin thiolesterase; UCH-L3
Gene Aliases: RGD1561196; UCH-6; UCH-L3; UCHL3
UniProt ID: (Human) P15374, (Mouse) Q9JKB1, (Rat) Q91Y78
Entrez Gene ID: (Chicken) 395626, (Human) 7347, (Dog) 476947, (Mouse) 50933, (Rat) 498560
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