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Application
FIGURE: 1 / 3
UCN2 Antibody (PA5-66875) in ICC/IF
Immunofluorescent staining of UCN2 in human cell line U-251 MG shows localization to vesicles. Samples were probed using an UCN2 Polyclonal Antibody (Product # PA5-66875).
Product Details
PA5-66875
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human UCN2. Recombinant protein control fragment (Product #RP-105408).
Conjugate
Unconjugated
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2664478
Product Specific Information
Immunogen sequence: SPSAAPTWPWA AQSHCSPTRH PGSRIVLSLD VPIGLLQILL EQARARAARE QATTNARILA RV
Highest antigen sequence identity to the following orthologs - mouse 57%, rat 60%.
Target Information
UCN2 (Urocortin 2) is a Protein Coding gene. Diseases associated with UCN2 include Body Mass Index Quantitative Trait Locus 11. Among its related pathways are Signaling by GPCR and Presynaptic function of Kainate receptors. Gene Ontology (GO) annotations related to this gene include signaling receptor binding and G protein-coupled receptor binding. An important paralog of this gene is UCN3. This gene is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2 receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin II. [provided by RefSeq, Jul 2008]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: prepro-urocortin 2; Stresscopin-related peptide; Ucn II; Urocortin II; Urocortin-2; Urocortin-related peptide
Gene Aliases: SRP; UCN-II; UCN2; UCNI; UR; URP
UniProt ID: (Human) Q96RP3
Entrez Gene ID: (Human) 90226
Performance Guarantee
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