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Product Details
PA5-54986
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human UGCG. Recombinant protein control fragment (Product #RP-93000).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2649242
Product Specific Information
Immunogen sequence: RLHLNKKATD KQPYSKLPGV SLLKPLKGVD PNLINNLETF FELDYPKYEV LLCVQDHDDP AIDVCKKLLG KYPNVDARLF IGGKKVGINP KINNLMPGYE VAKYDLI
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 98%.
Target Information
May serve as a "flippase" as well as a glucosyltransferase that transfers glucose to ceramide. It Catalyzes; UDP-glucose + Nacylsphingosine = UDP + D-glucosyl-N-acylsphingosine. Ceramide Glycosyltransferase is the first step in the Glycosphingolipid synthesis; first glycosylation step. Glucosylceramide synthase (GlcT) and lactosylceramide synthase (GalT) are key enzymes for the synthesis of major glycosphingolipids of vertebrates.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ceramide glucosyltransferase; GCS; GLCT-1; Glucosylceramide synthase; Glycosylceramide synthase; UDP-glucose ceramide glucosyltransferase; UDP-glucose:N-acylsphingosine D-glucosyltransferase
Gene Aliases: GCS; GLCT1; UGCG
UniProt ID: (Human) Q16739
Entrez Gene ID: (Human) 7357
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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