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Application
FIGURE: 1 / 5
ULK2 Antibody (MA5-31948) in WB
Western blot analysis of ULK2 in NIH/3T3 (1), HepG2 (2), SK-Hep-1 (3), SK-OV-3 (4), C6 (5), PC-12 (6), and MCF-7 (7) cell lysate. Samples were incubated with ULK2 monoclonal antibody (Product # MA5-31948) using a dilution of 1:500-1:2000.
Product Details
MA5-31948
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
2H4B2
Immunogen
Purified recombinant fragment of human ULK2 (AA: 1-155) expressed in E. coli.
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2787571
Product Specific Information
MA5-31948 has been tested in indirect ELISA.
Target Information
ULK2, also known as ATG1B, is a key serine/threonine protein kinase probably acting at the most upstream step of autophagosome formation. Knockout of ULK2 results in a severe defect in the autophagy pathway. ULK2 is highly conserved among eukaryotes and shows high homology with its related protein ULK1. Both ULK1 and ULK2 form a complex with ATG13 and FIP200 that mediates TOR signaling and is essential for autophagy. Like ULK1, ULK2 is also thought to be involved in early neuronal growth and differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EC:2.7.11.1; Serine/threonine-protein kinase ULK2; Serine/threonine-protein kinase Unc51.2; Unc-51 like kinase 2; Unc-51-like kinase 2
Gene Aliases: A830085I22Rik; ATG1B; AU015340; KIAA0623; mKIAA0623; ULK2; Unc51.2
UniProt ID: (Human) Q8IYT8, (Mouse) Q9QY01
Entrez Gene ID: (Human) 9706, (Mouse) 29869, (Rat) 303206
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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