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Immunogen sequence: EMTFPGERI YEVVRPLVSL LHLNCSGLQN FEALMALTNL AGISERLRQK ILKEKAVPMI EGYMFEEHEM IRRAATECMC NLAMSKEVQD LFEAQGNDRL KLLVLYSGED DELLQRAAAG GLAMLTSMRP TLCSRIPQVT THWLEILQAL LLSSNQELQH RGAVVVLNMV EASREIASTL MESEMMEILS VLAKGDHSPV TRAAAACLDK AVEYGLIQPN QDGE (722-944 aa encoded by B C006214)
UNC45A, also named as SMAP1, acts as co-chaperone for HSP90. UNC45A prevents the stimulation of HSP90AB1 ATPase activity by AHSA1. It is a positive factor in promoting PGR function in the cell. It is necessary for proper folding of myosin and necessary for normal cell proliferation, normal myotube formation and myosin accumulation during muscle cell development. UNC45A plays a role in erythropoiesis in stroma cells in the spleen.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: GCUNC-45; general cell UNC45; Protein unc-45 homolog A; SMAP-1; smooth muscle cell associated protein-1; Smooth muscle cell-associated protein 1; Stromal membrane-associated protein 1; unc-45 homolog A; UNC-45A
Gene Aliases: AW538196; GC-UNC45; GCUNC-45; GCUNC45; IRO039700; RGD1305357; SMAP-1; SMAP1; UNC-45A; UNC45A
UniProt ID: (Human) Q9H3U1, (Mouse) Q99KD5, (Rat) Q32PZ3
Entrez Gene ID: (Human) 55898, (Mouse) 101869, (Rat) 308759
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