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Immunogen sequence: KARPMEGSLE EPQETSHSGS DKEHRDVERS QEQESEAQRY HVDDGRRHRA HHEPERLSRR SEDEQRWGKG PGQDRGKK
Highest antigen sequence identity to the following orthologs: Mouse - 46%, Rat - 47%.
UPF3A is part of a multiprotein post-splicing mRNP complex involved in both mRNA nuclear export and mRNA surveillance. UPF3A is involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: hUpf3; Nonsense mRNA reducing factor 3A; Regulator of nonsense transcripts 3A; Up-frameshift suppressor 3 homolog A
Gene Aliases: HUPF3A; RENT3A; UPF3; UPF3A
UniProt ID: (Human) Q9H1J1
Entrez Gene ID: (Human) 65110
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