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PA1-958 detects VDAC2 in mouse, rat, human, rabbit, and bovine samples.
PA1-958 has been used successfully in Western blot procedures. By Western blot PA1-958 is specific for the ~30 kDa VDAC2 protein.
The PA1-958 immunogen corresponds to chicken recombinant VDAC2 protein.
This gene encodes a member of the voltage-dependent anion channel pore-forming family of proteins that are considered the main pathway for metabolite diffusion across the mitochondrial outer membrane. The encoded protein is also thought to be involved in the mitochondrial apoptotic pathway via regulation of BCL2-antagonist/killer 1 protein activity. Pseudogenes have been identified on chromosomes 1, 2, 12 and 21, and alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: B36-VDAC; FLJ23841; Outer mitochondrial membrane protein porin 2; RP11-375G3.1; VDAC-2; VDAC-6; voltage-dependent anion channel 2; Voltage-dependent anion-selective channel protein 2; Voltage-dependent anion-selective channel protein 6
Gene Aliases: mVDAC2; mVDAC6; POR; VDAC; VDAC2; Vdac6
UniProt ID: (Bovine) P68002, (Rabbit) P68003, (Human) P45880, (Mouse) Q60930, (Rat) P81155
Entrez Gene ID: (Bovine) 282120, (Rabbit) 100009473, (Human) 7417, (Mouse) 22334, (Rat) 83531
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