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Peptide Sequence: SILDEYENSL SRSAVLQPGC PSVGIPHSGY VNAQLEKEVP IFTKQRIDFT PSERITSLVV SSNQLCMSLG KDTLLRIDLG KANEPNHVEL GRKDDAKV
VPS18 is a vesicle mediated protein that plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps18 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: hVPS18; vacuolar protein sorting 18 homolog; vacuolar protein sorting protein 18; Vacuolar protein sorting-associated protein 18 homolog; VPS18 CORVET/HOPS core subunit
Gene Aliases: KIAA1475; PEP3; VPS18
UniProt ID: (Human) Q9P253
Entrez Gene ID: (Human) 57617
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