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This target displays homology in the following species: Cow: 93%; Dog: 86%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 100%; Rat: 100%
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Studies of the related mouse protein suggest that the encoded protein may play a role in the process of ossification.
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Protein Aliases: WD repeat domain 8; WD repeat-containing protein 8; WD repeat-containing protein antisense to TP73; WD repeat-containing protein antisense to TP73 gene; WD repeat-containing protein WRAP73
Gene Aliases: 2610044M17Rik; 5330425N03Rik; Dd57; Wdr8; Wrap73
UniProt ID: (Mouse) Q9JM98
Entrez Gene ID: (Mouse) 59002
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