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This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster.
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Protein Aliases: protease inhibitor WAP2; Putative protease inhibitor WAP12; single WAP motif protein 2; WAP four-disulfide core domain protein 12; Whey acidic protein 2
Gene Aliases: C20orf122; dJ211D12.4; SWAM2; UNQ544/PRO844; WAP2; WFDC12
UniProt ID: (Human) Q8WWY7
Entrez Gene ID: (Human) 128488
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