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Sequence of this protein is as follows: MATDSGDPAS TEDSEKPDGI SFENRVPQVA ATLTVEARLK EKNSTFSASG ETVERKRFFR KSVEMTEDDK VAESSPKDER IKAAMNIPRV DKLPSNVLRG
WNK3 is a serine/threonine kinase involved in signal transduction and cellular communication. Members of the 'with no lysine' kinase family, such as WNK3, are serine-threonine protein kinases that lack the almost invariant catalytic lysine in subdomain II, which is important for binding ATP in the catalytic site. Instead, these kinases have a conserved lysine in subdomain I that is thought to provide this function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: PRKWNK 3; Protein kinase lysine-deficient 3; Protein kinase with no lysine 3; Serine/threonine-protein kinase WNK3; WNK 3
Gene Aliases: KIAA1566; PRKWNK3; WNK3
UniProt ID: (Human) Q9BYP7
Entrez Gene ID: (Human) 65267
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