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Application
FIGURE: 1 / 3
WWC2 Antibody (PA5-71284) in WB
Journal of oncology 2022 -
Figure 3 miR-146a-5p downregulates WWC2 to activate the Hippo-YAP signaling pathway. (a) The Venn map of the intersection of target genes obtained from the TargetScan, miRWalk, miRDB, and ENCORI databases and differentially expressed genes in GEPIA2 database in cervical cancer. (b) Analysis of the expression of WWC2 in cervical cancer by GEPIA2 database. Red represents cervical cancer samples, and gray repr... View More
Product Details
PA5-71284
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
synthetic peptide directed towards the C-terminal region of human WWC2
Conjugate
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2691041
Product Specific Information
This target displays homology in the following species: Cow: 92%; Dog: 100%; Guinea Pig: 92%; Horse: 93%; Human: 100%; Mouse: 92%; Pig: 100%; Rat: 92%; Yeast: 83%
Target Information
This gene encodes a member of the WW-and-C2-domain-containing family of proteins. Members of this family have two N-terminal WW domains that mediate binding to target proteins harboring L/PPxY motifs, an internal C2 domain for membrane association, and C-terminal alpha protein kinase C binding sites and class III PDZ domain-interaction motifs. Proteins of this family are able to form homo- and heterodimers and to modulate hippo pathway signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: BH-3-only member B; BH3-only member B protein; Protein WWC2; WW domain-containing protein 2; WW, C2 and coiled-coil domain containing 2
Gene Aliases: BOMB; WWC2
UniProt ID: (Human) Q6AWC2
Entrez Gene ID: (Human) 80014
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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