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Invitrogen

XIAP Polyclonal Antibody

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View all (38) XIAP antibodies

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Catalog # PA5-29644

Price (EUR)

524,00

100 µL

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Datasheet

Protocols

Questions & Answers

Tech Support

Antibody Testing Data (3)
Advanced Verification (1)

Application

XIAP Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 4

XIAP Antibody (PA5-29644) in ICC/IF

Immunocytochemistry analysis of XIAP in methanol-fixed HeLa. Samples were incubated with XIAP polyclonal antibody (Product # PA5-29644) using a dilution of 1:100.

XIAP Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Product Image Gallery

XIAP Antibody — Antibody specificity was demonstrated by knocking out the target protein. XIAP knockout (KO) HeLa cell lysate shows decrease in signal intensity in western blot application using XIAP Polyclonal Antibody (Product # PA5-29663). {KO}

Product Details

PA5-29644

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:3,000

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:1,000

Immunocytochemistry (ICC/IF)

1:100-1:1,000

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human XIAP. The exact sequence is proprietary.

Conjugate

Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

0.1M tris glycine, pH 7, with 10% glycerol

Contains

0.01% thimerosal

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_2547119

Product Specific Information

Recommended positive controls: HeLa.

Predicted reactivity: Mouse (88%), Rat (90%), Dog (88%), Pig (92%), Rabbit (94%), Bovine (86%).

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

ATP synthase is extremely conserved through evolution and can be found in plants, fungi, bacteria, and animals. The ATP synthase enzyme is a transmembrane protein responsible for driving the reversible reaction from ADP+ phosphate to ATP. This reaction is accomplished by a flux of protons across the membrane as a result of electron transfer. The ATP synthase protein has two main sections; the F1 ATP-ase (soluble) and the F0 ATP-ase (membrane embedded). The F1 section consists of the alpha, beta, gamma, delta, and epsilon subunits. While the F0 consists of a, b, and c subunits.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Baculoviral IAP repeat-containing protein 4; BIR4; E3 ubiquitin-protein ligase XIAP; HILP; IAP homolog A; IAP-3; IAP-like protein; ILP; Inhibitor of apoptosis protein 3; RING-type E3 ubiquitin transferase XIAP; RP1-315G1.5; X-linked IAP; X-linked inhibitor of apoptosis protein; X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase

Gene Aliases: 1110015C02Rik; Aipa; API3; BIRC4; hIAP-3; hIAP3; IAP-3; IAP3; ILP-1; ILP1; MIHA; XIAP; XLP2

UniProt ID: (Human) P98170, (Mouse) Q60989

Entrez Gene ID: (Human) 331, (Mouse) 11798

Function(s)

ubiquitin-protein transferase activity protein binding zinc ion binding ligase activity identical protein binding cysteine-type endopeptidase inhibitor activity involved in apoptotic process ubiquitin protein ligase activity protease binding UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity ribosomal S6-glutamic acid ligase activity coenzyme F420-0 gamma-glutamyl ligase activity coenzyme F420-2 alpha-glutamyl ligase activity metal ion binding protein-glycine ligase activity protein-glycine ligase activity, initiating protein-glycine ligase activity, elongating tubulin-glycine ligase activity protein-glutamic acid ligase activity tubulin-glutamic acid ligase activity scaffold protein binding protease inhibitor

Process(es)

apoptotic process cellular response to DNA damage stimulus Wnt signaling pathway protein ubiquitination regulation of BMP signaling pathway positive regulation of protein ubiquitination regulation of cell proliferation negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process regulation of innate immune response regulation of inflammatory response copper ion homeostasis regulation of nucleotide-binding oligomerization domain containing signaling pathway positive regulation of canonical Wnt signaling pathway mitotic spindle assembly positive regulation of protein linear polyubiquitination inhibition of cysteine-type endopeptidase activity involved in apoptotic process negative regulation of neuron apoptotic process neuron apoptotic process

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