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Peptide sequence: LHLLQLGPLF RCFEVFCIYF QSGNNEEPYV SITKKRQMPK NGLSEEIEKE
Sequence homology: Cow: 100%; Dog: 85%; Guinea Pig: 85%; Human: 100%; Mouse: 100%; Rabbit: 85%; Rat: 100%
The XK protein is a membrane-bound protein associated with the endoplasmic reticulum (ER) and forms part of the ER membrane complex (EMC), which is critical for various cellular processes. This protein is involved in the insertion, folding, and assembly of membrane proteins in eukaryotic cells. The XK protein's role in the ER highlights its importance in maintaining proper cell function, as the ER is integral in protein synthesis, lipid metabolism, and calcium storage. Furthermore, the XK protein's involvement in these processes underscores its significance in cellular homeostasis and its potential contribution to pathologies when mutated or dysfunctional.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Endoplasmic reticulum membrane adapter protein XK; Kell blood group precursor (McLeod phenotype); Kell complex 37 kDa component; Kx antigen; Membrane transport protein XK; neuroacanthocytosis; neurocanthocytosis; XK, Kell blood group complex subunit (McLeod syndrome); XK-related protein 1
Gene Aliases: KX; MCLDS; NA; NAC; X1k; XK; XKR1; XRG1
UniProt ID: (Human) P51811
Entrez Gene ID: (Human) 7504
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