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Product Details
PA5-53900
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human XK. Recombinant protein control fragment (Product #RP-92164).
Conjugate
Unconjugated
Form
Liquid
Concentration
0.4 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2649682
Product Specific Information
Immunogen sequence: DLSRDRPLVL LLHLLQLGPL FRCFEVFCIY FQSGNNEEPY VSITKKRQMP KNGLSEEIEK EVGQAEGKLI THRSAFSRA
Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 87%.
Target Information
The XK protein is a membrane-bound protein associated with the endoplasmic reticulum (ER) and forms part of the ER membrane complex (EMC), which is critical for various cellular processes. This protein is involved in the insertion, folding, and assembly of membrane proteins in eukaryotic cells. The XK protein's role in the ER highlights its importance in maintaining proper cell function, as the ER is integral in protein synthesis, lipid metabolism, and calcium storage. Furthermore, the XK protein's involvement in these processes underscores its significance in cellular homeostasis and its potential contribution to pathologies when mutated or dysfunctional.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Endoplasmic reticulum membrane adapter protein XK; Kell blood group precursor (McLeod phenotype); Kell complex 37 kDa component; Kx antigen; Membrane transport protein XK; neuroacanthocytosis; neurocanthocytosis; XK, Kell blood group complex subunit (McLeod syndrome); XK-related protein 1
Gene Aliases: KX; MCLDS; NA; NAC; X1k; XK; XKR1; XRG1
UniProt ID: (Human) P51811
Entrez Gene ID: (Human) 7504
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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