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Application
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YOD1 Antibody (PA5-55851) in ICC/IF
Immunofluorecent analysis of YOD1 in human cell line A-431 using YOD1 Polyclonal Antibody (Product # PA5-55851). Staining shows localization to nucleoplasm, plasma membrane and cytosol.
Product Details
PA5-55851
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human YOD1. Recombinant protein control fragment (Product #RP-94483).
Conjugate
Unconjugated
Form
Liquid
Concentration
0.4 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2649735
Product Specific Information
Immunogen sequence: QRNFPDPDTP PLTIFSSNDD IVLVQALELA DEARRRRQFT DVNRFTLRCM VCQKGLTGQA EAREHAKETG HTNFGEV
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%.
Target Information
Deubiquitinating enzymes (DUBs) are proteases that specifically cleave ubiquitin linkages, negating the action of ubiquitin ligases. DUBA8 belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DUBA-8; HIN-7; HIV-1-induced protease 7; hsHIN7; OTU domain containing 2; OTU domain-containing protein 2; Ubiquitin thioesterase OTU1; YOD1 OTU deubiquinating enzyme 1 homolog ( yeast)
Gene Aliases: DUBA8; HIN7; OTUD2; PRO0907; YOD1
UniProt ID: (Human) Q5VVQ6
Entrez Gene ID: (Human) 55432
thiol-dependent ubiquitin-specific protease activity
protein binding
ubiquitin protein ligase binding
metal ion binding
Lys63-specific deubiquitinase activity
ubiquitin-specific protease activity involved in negative regulation of retrograde protein transport, ER to cytosol
Lys48-specific deubiquitinase activity
cysteine protease
ER-associated ubiquitin-dependent protein catabolic process
endoplasmic reticulum unfolded protein response
protein K29-linked deubiquitination
protein K11-linked deubiquitination
protein K63-linked deubiquitination
protein K48-linked deubiquitination
negative regulation of retrograde protein transport, ER to cytosol
protein K27-linked deubiquitination
protein K33-linked deubiquitination
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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