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            • Primary Antibodies ›
            • Pokemon Antibodies

            Bethyl Laboratories

            ZBTB7/FBI-1 Polyclonal Antibody

            View all (17) Pokemon antibodies
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            Cite ZBTB7/FBI-1 Polyclonal Antibody

            • Antibody Testing Data (2)
            Application
            ZBTB7/FBI-1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Group 53 Created with Sketch.

            FIGURE: 1 / 2

            ZBTB7/FBI-1 Antibody (A300-549A) in IHC (P)

            Detection of human ZBTB7/FBI-1 by immunohistochemistry. Sample: FFPE section of human colon carcinoma. Antibody: Affinity purified rabbit anti-ZBTB7/FBI-1 (Product # A300-549A) (Lot 1) used at a dilution of 1:200 (1 µg/mL). Detection: DAB.
            View Product

            ZBTB7/FBI-1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            ZBTB7/FBI-1 Antibody in Western Blot (WB)

            Product Details

            A300-549A

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            1:2,000-1:10,000
            -

            Immunohistochemistry (IHC)

            1:100-1:500
            -

            Immunohistochemistry (Paraffin) (IHC (P))

            1:100-1:500
            -

            Immunoprecipitation (IP)

            2-5 µg/mg lysate
            -
            Product Specifications

            Species Reactivity

            Human

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            Region between residue 525 and the C-terminus (residue 584) of Human ZBTB7 (Factor Binding IST protein 1).
            View immunogen

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            0.20 mg/mL

            Purification

            Antigen affinity chromatography

            Storage buffer

            TBS, pH 7.0 to 8.0, with 0.1% BSA

            Contains

            0.09% sodium azide

            Storage conditions

            4°C

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            Product Specific Information

            The recommended shelf life for this product is 1 year from date of receipt.

            Application Note: For IHC, epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.

            Target Information

            Plays a key role in the instruction of early lymphoid progenitors to develop into B lineage by repressing T-cell instructive Notch signals. Specifically represses the transcription of the CDKN2A gene. Efficiently abrogates E2F1-dependent CDKN2A transactivation/de-repression. Binds to the consensus sequence 5'-[GA][CA]GACCCCCCCCC-3'.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            References (0)

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            Cite this product

            Bioinformatics

            Protein Aliases: DKFZp547O146; Factor binding IST protein 1; Factor that binds to inducer of short transcripts protein 1; FBI-1; HIV-1 1st-binding protein 1; HIV-1 inducer of short transcripts binding protein; Leukemia/lymphoma-related factor; lymphoma related factor; MGC99631; POK erythroid myeloid ontogenic factor; POZ and Krueppel erythroid myeloid ontogenic factor; TIP21; TTF-I-interacting peptide 21; zi; zinc finger and BTB domain containing 7A, HIV-1 inducer of short transcripts binding protein; Zinc finger and BTB domain-containing protein 7A; Zinc finger protein 857A

            View more View less

            Gene Aliases: FBI-1; FBI1; LRF; pokemon; TIP21; ZBTB7; ZBTB7A; ZNF857A

            View more View less

            UniProt ID: (Human) O95365

            View more View less

            Entrez Gene ID: (Human) 51341

            View more View less

            Function(s)

            RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding DNA binding protein binding histone acetyltransferase binding metal ion binding

            Process(es)

            negative regulation of transcription from RNA polymerase II promoter transcription, DNA-templated multicellular organism development cell differentiation regulation of osteoclast differentiation negative regulation of transcription, DNA-templated
            It has to be done as per old AB suggested Products section.
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            Performance Guarantee

            If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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