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Product Details
PA5-110590
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 150-230 of human ZC3H12D (NP_997243.2).
Conjugate
Unconjugated
Form
Liquid
Concentration
1.50 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2856001
Product Specific Information
Immunogen sequence: QHVLAELERQ AVLVYTPSRK VHGKRLVCYD DRYIVKVAYE QDGVIVSNDN YRDLQSENPE WKWFIEQRLL MFSFVNDRFM P
Target Information
ZC3H12D, also known as MCPIP4, is a member of a family of novel CCCH-zinc finger proteins that includes ZC3H12A, a protein that is thought to be involved in macrophage activation, host immunity and inflammatory diseases. ZC3H12D is highly expressed in spleen, intestine, and colon. Similar to ZC3H12A and ZC3H12C, ZC3H12D expression in murine macrophages is also increased after treatment with lipopolysaccharide (LPS), although not to the same level as ZC3H12A. This pattern of expression was not duplicated in human-derived macrophages, suggesting it also may play a different role in host immunity and inflammatory response.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MCP-induced protein 4; p34; Probable ribonuclease ZC3H12D; RP1-281H8.5; Transformed follicular lymphoma; Transformed follicular lymphoma homolog; tumor suppressor TFL; zc3h12d; Zinc finger CCCH domain-containing protein 12D; zinc finger CCCH-type containing 12D
Gene Aliases: C6orf95; D730019B10Rik; dJ281H8.1; MCPIP4; p34; TFL; ZC3H12D
UniProt ID: (Human) A2A288, (Mouse) Q8BIY3
Entrez Gene ID: (Human) 340152, (Mouse) 237256, (Rat) 308266
Performance Guarantee
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