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            • Primary Antibodies ›
            • ZC3HAV1 Antibodies

            Proteintech

            ZC3HAV1 Polyclonal Antibody

            33 References
            View all (10) ZC3HAV1 antibodies
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            Catalog # 16820-1-AP
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            Price (EUR)
            437,00
            150 µL
             
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            Cite ZC3HAV1 Polyclonal Antibody

            • Antibody Testing Data (7)
            Application
            ZC3HAV1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Group 53 Created with Sketch.

            FIGURE: 1 / 7

            ZC3HAV1 Antibody (16820-1-AP) in IHC (P)

            Immunohistochemistry of paraffin-embedded human kidney tissue slide using 16820-1-AP ( ZC3HAV1 Antibody) at dilution of 1:50 (under 40x lens).
            View Product

            ZC3HAV1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            ZC3HAV1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            ZC3HAV1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            ZC3HAV1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            ZC3HAV1 Antibody in Western Blot (WB)
            ZC3HAV1 Antibody in Western Blot (WB)
            ZC3HAV1 Antibody in Immunoprecipitation (IP)

            Product Details

            16820-1-AP

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            1:1,000-1:8,000
            View 22 publications 22 publications

            Immunohistochemistry (IHC)

            -
            View 2 publications 2 publications

            Immunohistochemistry (Paraffin) (IHC (P))

            1:20-1:200
            -

            Immunocytochemistry (ICC/IF)

            -
            View 3 publications 3 publications

            Immunoprecipitation (IP)

            0.5-4.0 µg
            View 3 publications 3 publications

            RNA Immunoprecipitation (RIP)

            -
            View 1 publication 1 publication

            Not applicable (N/A)

            -
            View 2 publications 2 publications
            Product Specifications

            Species Reactivity

            Human, Mouse, Rat

            Published species

            Human, Mouse

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            ZC3HAV1 Fusion Protein Ag10364 (1-351 aa encoded by BC025308)
            View immunogen

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            0.37 mg/mL

            Purification

            Antigen affinity chromatography

            Storage buffer

            PBS, pH 7.3, with 50% glycerol

            Contains

            0.02% sodium azide

            Storage conditions

            -20°C

            Shipping conditions

            Wet ice (domestic); Dry ice (international)

            Product Specific Information

            Immunogen sequence: MADPEVCCF ITKILCAHGG RMALDALLQE IALSEPQLCE VLQVAGPDRF VVLETGGEAG ITRSVVATTR ARVCRRKYCQ RPCDNLHLCK LNLLGRCNYS QSERNLCKYS HEVLSEENFK VLKNHELSGL NKEELAVLLL QSDPFFMPEI CKSYKGEGRQ QICNQQPPCS RLHICDHFTR GNCRFPNCLR SHNLMDRKVL AIMREHGLNP DVVQNIQDIC NSKHMQKNPP GPRAPSSHRR NMAYRARSKS RDRFFQGSQE FLASASASAE RSCTPSPDQI SHRASLEDAP VDDLTRKFTY LGSQDRARPP SGSSKATDLG GTSQAGTSQR FLENGSQEDL LHGNPGSTYL AS (1-351 aa encoded by BC025308)

            Target Information

            The zinc finger antiviral protein (ZC3HAV1) is a CCCH type zinc finger protein that induces an innate immunity to infections by retrovirus by preventing the accumulation of viral RNAs in the cytoplasm and recruits the RNA processing exosome to degrade target RNAs, thereby inhibiting virus replication. ZC3HAV1 is localized in the cytoplasm at steady state, but shuttles between nucleus and cytoplasm in a XPO1-dependent manner. ZAP is a direct target gene of IRF3 action in cellular antiviral responses.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            Bioinformatics

            Protein Aliases: ADP-ribosyltransferase diphtheria toxin-like 13; ARTD13; CCCH-type zinc finger antiviral protein (Zap); Inactive Poly [ADP-ribose] polymerase 13; PARP13; rZAP; ZAP; Zinc finger antiviral protein; Zinc finger CCCH domain-containing protein 2; Zinc finger CCCH-type antiviral protein 1; zinc finger CCCH-type, antiviral 1

            View more View less

            Gene Aliases: 1200014N16Rik; 2900058M19Rik; 9130009D18Rik; 9830115L13Rik; ARTD13; D6Bwg1452e; FLB6421; PARP13; PRO1677; ZAP; ZC3H2; ZC3HAV1; ZC3HDC2

            View more View less

            UniProt ID: (Human) Q7Z2W4, (Mouse) Q3UPF5

            View more View less

            Entrez Gene ID: (Human) 56829, (Rat) 252832, (Mouse) 78781

            View more View less

            Function(s)

            NAD+ ADP-ribosyltransferase activity protein binding poly(A) RNA binding metal ion binding cadherin binding involved in cell-cell adhesion RNA binding DEAD/H-box RNA helicase binding

            Process(es)

            response to virus positive regulation of type I interferon production positive regulation of interferon-alpha production positive regulation of interferon-beta production suppression by virus of host molecular function positive regulation of I-kappaB kinase/NF-kappaB signaling negative regulation of viral genome replication innate immune response regulation of defense response to virus by host defense response to virus positive regulation of mRNA catabolic process cellular response to exogenous dsRNA positive regulation of RIG-I signaling pathway immune system process positive regulation of ATPase activity cell-cell adhesion
            It has to be done as per old AB suggested Products section.
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