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Product Details
25629-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ZCRB1 Fusion Protein Ag22095 (1-217 aa encoded by BC022543)
Conjugate
Form
Liquid
Concentration
0.37 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSGGLAPSK STVYVSNLPF SLTNNDLYRI FSKYGKVVKV TIMKDKDTRK SKGVAFILFL DKDSAQNCTR AINNKQLFGR VIKASIAIDN GRAAEFIRRR NYFDKSKCYE CGESGHLSYA CPKNMLGERE PQKKKEKKKK KKAPEPEEEI EEVEESEDEG EDPALDSLSQ AIAFQQAKIE EEQKKWKPSS GVPSTSDDSR RPRIKKSTYF SDEEELSD (1-217 aa encoded by BC022543)
Target Information
ZCRB1 is a nuclear protein first identified in a differential display screen involving morphine-dependence-related genes. Its expression is increased following morphine treatment and has been observed to be elevated in HepG2 cells. ZCRB1 contains a CCHC-type zing finger RNA-binding motif and can interact with the DBA-binding domain of the stem cell regulator C/EBP transcription factors. ZCRB1 was identified as one of the protein components of U11/U12 snRNPs, which are components of U12-type spliceosome and function as a molecular bridge connecting both ends of the intron, suggesting ZCRB1 may play a key role in U12-type splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: MADP-1; MGC26805; U11/U12 small nuclear ribonucleoprotein 31 kDa protein; U11/U12 snRNP 31 kDa protein; U11/U12 snRNP 31K; U11/U12-31K; zinc finger CCHC-type and RNA binding motif 1; Zinc finger CCHC-type and RNA-binding motif-containing protein 1
Gene Aliases: 2700088M22Rik; MADP-1; MADP1; RBM36; SNRNP31; ZCCHC19; ZCRB1
UniProt ID: (Human) Q8TBF4, (Mouse) Q9CZ96
Entrez Gene ID: (Human) 85437, (Mouse) 67197
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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