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Application
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ZIC2 Antibody (PA5-23446) in WB
Western blot analysis of ZIC2 in HepG2 cell lysate using 1) pre-bleed, and 2) this antibody. Samples were incubated in ZIC2 polyclonal antibody (Product # PA5-23446) followed by a goat anti-rabbit Ig HRP secondary antibody. PicoTect ECL substrate solution was used for this test.
Product Details
PA5-23446
Product Specifications
Species Reactivity
Bovine,
Dog,
Chicken,
Horse,
Human,
Mouse,
Non-human primate
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A portion of amino acid 350 to 400 of human ZIC2
Conjugate
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS with 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2540946
Target Information
ZIC2 (zinc finger protein of the cerebellum 2) is a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. In mouse, knockout of Zic1 leads to aplasia of cerebellum and skeletal abnormalities. Mutation in Zic2 and Zic3 in mouse and/or human cause holoprosencephaly and heterotaxis, respectively. Holoprosencephaly is the most common structural anomaly of the human brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cerebellum zinc finger protein 2; GENA 29; kumba; odd-paired homolog; Zic family member 2 (odd-paired homolog, Drosophila); Zinc finger protein of the cerebellum 2; Zinc finger protein ZIC 2; zinc finger protein Zic2
Gene Aliases: HPE5; Ku; ZIC2
UniProt ID: (Human) O95409
Entrez Gene ID: (Bovine) 514433, (Dog) 485533, (Horse) 100062051, (Human) 7546, (Chicken) 428021, (Mouse) 22772
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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