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Invitrogen
ZMYM4 Polyclonal Antibody
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Application
FIGURE: 1 / 1
ZMYM4 Antibody (PA5-89455) in WB
Western blot analysis of ZMYM4 in extracts of various cell lines. Samples were incubated with ZMYM4 Polyclonal antibody (Product # PA5-89455) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
Product Details
PA5-89455
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 35-230 of human ZMYM4 (NP_0050862)
Conjugate
Unconjugated
Form
Liquid
Concentration
0.44 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2805579
Product Specific Information
Immunogen sequence: TEMSEDIDHN LTPTLDSMSY GMPNQTGSEN SLLDEDDYFL NSGDLAGIPV VGSDNEDEQD FSSKDNLVSS IHTDDSLEVE RRVTQHESDN ENEIQIQNKL KKDFPKQFDQ VSVFKSIRKD FSLVRENSKE TFSGKEKNRD LTYEREKRLD KPHKDLDSRL KSSFFDKAAN QVEETLHTHL PQTPETNFRD SSYPFA; Positive Samples: 293T, HepG2, U87, HeLa
Target Information
Zinc-finger proteins contain DNA-binding domains characterized by the unique role of zinc and have a wide variety of functions such as transcriptional activation or repression. The protein folding and the DNA binding ability are governed by the coordination of a zinc ion. It has been found to be overexpressed in human lung adenocarcinomas and squamous cell carcinomas, and the overexpression of a fragment of the 3'UTR of the ZMYM4 mRNA termed Cell Death Inhibiting RNA (CDIR) protects HeLa cells from IFN-gamma-induced apoptosis, suggesting that ZMYM4 may play a role in tumorigenesis.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cell death inhibiting RNA; MYM type 4; Zinc finger MYM-type protein 4; Zinc finger protein 262; zinc finger, MYM-type 4
Gene Aliases: CDIR; KIAA0425; MYM; ZMYM4; ZNF198L3; ZNF262
UniProt ID: (Human) Q5VZL5
Entrez Gene ID: (Human) 9202
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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