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Zinc, an essential element required for cell proliferation and differentiation, plays a role in a diverse array of cellular functions, including acting as a cofactor for numerous enzymes and transcription factors and as a neuroregulator. The zinc transporter (ZnT) family regulates the supply of zinc within cells, and its members are characterized by containing six membrane-spanning domains, a large histidine-rich intracellular loop, and a C-terminal tail. ZnT-1, a ubiquitous protein of approximately 60 kDa, localizes to the plasma membrane to aid in the export of zinc out of cells.
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Protein Aliases: Proton-coupled zinc antiporter SLC30A1; solute carrier family 30 (zinc transporter), member 1; Solute carrier family 30 member 1; solute carrier family 30, member 1; Zinc transporter 1; ZnT-1
Gene Aliases: AI839647; C130040I11Rik; SLC30A1; ZNT1; ZRC1
UniProt ID: (Human) Q9Y6M5, (Rat) Q62720, (Mouse) Q60738
Entrez Gene ID: (Human) 7779, (Rat) 58976, (Mouse) 22782
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