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Invitrogen
alpha-II Spectrin Monoclonal Antibody (3D7)
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Application
FIGURE: 1 / 3
alpha-II Spectrin Antibody (MA5-18118) in ICC/IF
Immunocytochemistry analysis of SPTAN1 in neurons and glia cells showing specific axonal and dendritic labeling with alpha-II Spectrin monoclonal antibody (Product # MA5-18118) using a dilution of 1:500 (green), nuclear staining with DAPI (blue).
Product Details
MA5-18118
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
3D7
Immunogen
Recombinant contstruct containing the 7th, 8th, 9th repeats of human alpha II spectrin
Conjugate
Unconjugated
Form
Liquid
Concentration
~1 mg/mL
Purification
Protein G
Storage buffer
PBS with 50% glycerol
Contains
5mM sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2539492
Product Specific Information
This antibody contains enough material to conduct 10 mini-Western blots.
Target Information
SPTAN1 (spectrin alpha chain, non-erythrocytic 1) is a part of the spectrin family of filamentous cytoskeletal proteins. They function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. SPTAN1 has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: (ALPHA)II-SPECTRIN; a--fodrin; alpha; alpha II spectrin; alpha-fodrin; Alpha-II spectrin; alpha-spectrin 2; alpha-spectrin 2, brain; brain; brain alpha-spectrin; FLJ44613; Fodrin alpha chain; inhibitory protein factor; noerythroid alpha-spectrin 2; Non erythrocytic spectrin alpha; non-erythrocytic 1 (alpha-fodrin); non-erythroid alpha chain; nonerythroid alpha-spectrin 2; Spectrin; Spectrin alpha; Spectrin alpha chain brain; spectrin alpha chain, brain; Spectrin alpha chain, non-erythrocytic 1; spectrin, non-erythroid alpha chain; Spectrin, non-erythroid alpha subunit
Gene Aliases: 2610027H02Rik; A2a; EIEE5; IPF; NEAS; Spna-2; Spna2; SPTA2; SPTAN1
UniProt ID: (Human) Q13813, (Rat) P16086
Entrez Gene ID: (Bovine) 540108, (Human) 6709, (Mouse) 20740, (Rat) 64159
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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