Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
This Antibody was verified by Knockout to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 4
Positive test controls include: 293T, HeLa, Mouse brain, Mouse testis, Mouse lung, Rat brain, Rat testis, Rat lung. The target is usually found in the following locations: Cytoplasm, cytoskeleton.
Beta actin is one of six actin isoforms which have been identified. Beta actin is a non-muscle cytoskeletal protein in all human cell types and is involved in cell motility, structure, and integrity. There are six different actin isoforms in human. The beta isoform of actin, along with gamma actin, coexist in most cell types as components of the cyto-skeleton. Beta actins are cytoplasmic proteins ubuquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of two stranded helix. Actins are highly conserved proteins that are involved in cell motility, structure and integrity. Because beta actin is ubiquitously expressed in all eukaryotic cells, it is frequently used as a loading control for assays involving protein detection, such as Western blotting. Antibodies to beta-actin provide a specific and useful tool in studying the intracellular distribution of beta-actin and the static and dynamic aspects of the cytoskeleton.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: actin, beta; Actin, cytoplasmic 1; B-ACTZF; Bact; actin; beta actin; beta cytoskeletal actin; Beta-actin; Beta-actin-1; cytoplasmic 1; cytoplasmic beta-actin; cytoskeletal beta actin; PS1TP5-binding protein 1
Gene Aliases: ACTB; actba; actin; Actx; B-ACTZF; Bact; bactin1; bactzf; beta-actin; BRWS1; E430023M04Rik; PS1TP5BP1; wu:fd18f05
UniProt ID: (Human) Q96B34, (Pig) Q6QAQ1, (Chicken) P60706, (Rat) P60711, (Mouse) P60710, (Zebrafish) Q7ZVI7
Entrez Gene ID: (Human) 60, (Pig) 414396, (Chicken) 396526, (Rat) 81822, (Mouse) 11461, (Zebrafish) 57934
Molecular Function:
actin and actin related protein
actin or actin-binding cytoskeletal protein
cytoskeletal protein
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support