Product References
Targeting NEDDylation is a Novel Strategy to Attenuate Cisplatin-induced Nephrotoxicity.
Cancer research communications
Jones TM,Espitia CM,Chipollini J,Lee BR,Wertheim JA,Carew JS,Nawrocki ST
MA5-16308 was used in Western Blotting to demonstrate that NEDDylation inhibition with pevonedistat is a novel approach to selectively prevent cisplatin-induced oxidative damage to the kidneys while simultaneously enhancing its anticancer efficacy.
Wed Feb 01 00:00:00 EST 2023
A tubulin binding molecule drives differentiation of acute myeloid leukemia cells.
iScience
Jackson TR,Vuorinen A,Josa-Culleré L,Madden KS,Conole D,Cogswell TJ,Wilkinson IVL,Kettyle LM,Zhang D,O'Mahony A,Gracias D,McCall L,Westwood R,Terstappen GC,Davies SG,Tate EW,Wynne GM,Vyas P,Russell AJ,Milne TA
Published figure using beta Tubulin Loading Control monoclonal antibody (Product # MA5-16308) in Western Blot
Fri Aug 19 00:00:00 EDT 2022
A tubulin binding molecule drives differentiation of acute myeloid leukemia cells.
iScience
Jackson TR,Vuorinen A,Josa-Culleré L,Madden KS,Conole D,Cogswell TJ,Wilkinson IVL,Kettyle LM,Zhang D,O'Mahony A,Gracias D,McCall L,Westwood R,Terstappen GC,Davies SG,Tate EW,Wynne GM,Vyas P,Russell AJ,Milne TA
Published figure using beta Tubulin Loading Control monoclonal antibody (Product # MA5-16308) in Western Blot
Fri Aug 19 00:00:00 EDT 2022
Transcorneal but not transpalpebral electrical stimulation disrupts mucin homeostasis of the ocular surface.
BMC ophthalmology
Yang M,Lennikov A,Chang K,Ashok A,Lee C,Cho KS,Utheim TP,Dartt DA,Chen DF
MA5-16308 was used in Western Blotting to conclude that TcES, but not TpES, induces corneal epithelial damage in mice by disrupting mucin homeostasis, thus TpES may represent a safer and more effective ES approach for treating retinal neurodegeneration clinically.
Thu Dec 15 00:00:00 EST 2022
Blockade of 20-hydroxyeicosatetraenoic acid receptor lowers blood pressure and alters vascular function in mice with smooth muscle-specific overexpression of CYP4A12-20-HETE synthase.
Journal of hypertension
Agostinucci K,Hutcheson R,Hossain S,Pascale JV,Villegas E,Zhang F,Adebesin AM,Falck JR,Gupte S,Garcia V,Schwartzman ML
MA5-16308 was used in Western Blotting to examine whether VSMC-targeted overexpression of CYP4A12, the primary 20-HETE-producing enzyme in mice, is sufficient to promote hypertension.
Tue Mar 01 00:00:00 EST 2022
Targets for Renal Carcinoma Growth Control Identified by Screening FOXD1 Cell Proliferation Pathways.
Cancers
Bond KH,Sims-Lucas S,Oxburgh L
MA5-16308 was used in Western Blotting to identify tractable pathways to target G2/M transition and inhibit ccRCC growth, demonstrates the applicability of these strategies across patient tumor replicas, and provides a platform for individualized patient testing of compounds that inhibit tumor growth.
Tue Aug 16 00:00:00 EDT 2022
Krüppel-like factor 7 influences translation and pathways involved in ribosomal biogenesis in breast cancer.
Breast cancer research : BCR
Lüchtenborg AM,Metzger P,Cosenza Contreras M,Oria V,Biniossek ML,Lindner F,Fröhlich K,Malyi A,Erbes T,Gensch N,Maurer J,Thomsen A,Boerries M,Schilling O,Werner M,Bronsert P
MA5-16308 was used in ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to identify the transcription factor Krüppel-like factor 7 (KLF7) as a regulator of ribosomal biogenesis and translation in breast cancer cells and tissue.
Mon Oct 03 00:00:00 EDT 2022
Direct modulation of microglial function by electrical field.
Frontiers in cell and developmental biology
Lennikov A,Yang M,Chang K,Pan L,Saddala MS,Lee C,Ashok A,Cho KS,Utheim TP,Chen DF
MA5-16308 was used in Immunocytochemistry-immunofluorescence to reveal a direct modulatory effect of ES on previously thought electrically non-responsive" microglia and suggest a new avenue of employing ES for anti-inflammatory therapy."
Sat Jul 01 00:00:00 EDT 2023
Promyelocytic leukemia protein targets MK2 to promote cytotoxicity.
EMBO reports
Chen IT,Chen HC,Lo YH,Lai PY,Hsieh FY,Wu YH,Shih HM,Lai MZ
MA5-16308 was used in ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to show that PML deficiency leads to enhanced TNF-induced MAPK-activated kinase 2 (MK2) activation and elevated RIPK1[S321] phosphorylation, which suppresses necrosome formation.
Mon Dec 06 00:00:00 EST 2021
Oxidative Stress Resistance 1 Gene Therapy Retards Neurodegeneration in the rd1 Mutant Mouse Model of Retinopathy.
Investigative ophthalmology & visual science
Sahu B,Leon LM,Zhang W,Puranik N,Periasamy R,Khanna H,Volkert M
MA5-16308 was used in Western Blot to show antioxidant regulatory gene OXR1 could protect neurons from oxidative stress and delay photoreceptor cell death.
Thu Sep 02 00:00:00 EDT 2021
Oxidative Stress Resistance 1 Gene Therapy Retards Neurodegeneration in the rd1 Mutant Mouse Model of Retinopathy.
Investigative ophthalmology & visual science
Sahu B,Leon LM,Zhang W,Puranik N,Periasamy R,Khanna H,Volkert M
MA5-16308 was used in Western Blot to show antioxidant regulatory gene OXR1 could protect neurons from oxidative stress and delay photoreceptor cell death.
Thu Sep 02 00:00:00 EDT 2021
Adipose Tissue-Derived Mesenchymal Stem Cell Concentrated Conditioned Medium Alters the Expression Pattern of Glutamate Regulatory Proteins and Aquaporin-4 in the Retina after Mild Traumatic Brain Injury.
Journal of neurotrauma
Jha KA,Gentry J,Del Mar NA,Reiner A,Sohl N,Gangaraju R
MA5-16308 was used in Western Blotting to suggest a novel neuroprotective role for ASC-CCM in the rescue of the visual deficits and pathologies of mTBI via restoration of Müller cell health.
Tue Jun 15 00:00:00 EDT 2021
Establishment of an induced pluripotent stem (iPS) cell line (SDUKIi006-A) from a 21-year old male patient diagnosed with atypical autism disorder.
Stem cell research
Kamand M,Forsberg SL,Thomassen M,Ilieva M,Meyer M,Svenningsen ÅF,Michel TM
MA5-16308 was used in In vitro Assay to show that characterization of the established cell line validated its expression of pluripotency markers, differentiation into the three germ layers, and the absence of chromosomal abnormalities.
Mon Mar 01 00:00:00 EST 2021
Hypoxia reduces cell attachment of SARS-CoV-2 spike protein by modulating the expression of ACE2, neuropilin-1, syndecan-1 and cellular heparan sulfate.
Emerging microbes & infections
Prieto-Fernández E,Egia-Mendikute L,Vila-Vecilla L,Bosch A,Barreira-Manrique A,Lee SY,García-Del Río A,Antoñana-Vildosola A,Jiménez-Lasheras B,Moreno-Cugnon L,Jiménez-Barbero J,Berra E,Ereño-Orbea J,Palazon A
Published figure using beta Tubulin Loading Control monoclonal antibody (Product # MA5-16308) in Western Blot
Wed Dec 01 00:00:00 EST 2021
A Cystine-Cysteine Intercellular Shuttle Prevents Ferroptosis in xCTKO Pancreatic Ductal Adenocarcinoma Cells.
Cancers
Meira W,Daher B,Parks SK,Cormerais Y,Durivault J,Tambutte E,Pouyssegur J,Vučetić M
Published figure using beta Tubulin Loading Control monoclonal antibody (Product # MA5-16308) in Western Blot
Sun Mar 21 00:00:00 EDT 2021
A Cystine-Cysteine Intercellular Shuttle Prevents Ferroptosis in xCTKO Pancreatic Ductal Adenocarcinoma Cells.
Cancers
Meira W,Daher B,Parks SK,Cormerais Y,Durivault J,Tambutte E,Pouyssegur J,Vučetić M
Published figure using beta Tubulin Loading Control monoclonal antibody (Product # MA5-16308) in Western Blot
Sun Mar 21 00:00:00 EDT 2021
Therapeutic Benefit of Galectin-1: Beyond Membrane Repair, a Multifaceted Approach to LGMD2B.
Cells
Vallecillo-Zúniga ML,Poulson PD,Luddington JS,Arnold CJ,Rathgeber M,Kartchner BC,Hayes S,Gill H,Valdoz JC,Spallino JL,Garfield S,Dodson EL,Arthur CM,Stowell SR,Van Ry PM
MA5-16308 was used in Immunocytochemistry to demonstrate that the reduced dimeric form of Gal-1 is responsible for inducing improvements to muscle membrane repair, while the monomeric form is responsible for changes in inflammation.
Wed Nov 17 00:00:00 EST 2021
Therapeutic Benefit of Galectin-1: Beyond Membrane Repair, a Multifaceted Approach to LGMD2B.
Cells
Vallecillo-Zúniga ML,Poulson PD,Luddington JS,Arnold CJ,Rathgeber M,Kartchner BC,Hayes S,Gill H,Valdoz JC,Spallino JL,Garfield S,Dodson EL,Arthur CM,Stowell SR,Van Ry PM
MA5-16308 was used in Immunocytochemistry to demonstrate that the reduced dimeric form of Gal-1 is responsible for inducing improvements to muscle membrane repair, while the monomeric form is responsible for changes in inflammation.
Wed Nov 17 00:00:00 EST 2021
Activity-dependent modulation of synapse-regulating genes in astrocytes.
eLife
Farhy-Tselnicker I,Boisvert MM,Liu H,Dowling C,Erikson GA,Blanco-Suarez E,Farhy C,Shokhirev MN,Ecker JR,Allen NJ
MA5-16308 was used in ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to investigate whether astrocyte diversity has any impact on the regulation of synapse formation or maturation in the visual cortex.
Wed Sep 08 00:00:00 EDT 2021
Recurrent Human Papillomavirus-Related Head and Neck Cancer Undergoes Metabolic Reprogramming and Is Driven by Oxidative Phosphorylation.
Clinical cancer research : an official journal of the American Association for Cancer Research
Vyas A,Harbison RA,Faden DL,Kubik M,Palmer D,Zhang Q,Osmanbeyoglu HU,Kiselyov K,Méndez E,Duvvuri U
MA5-16308 was used in ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to identify NRF2 as a driver of tumor growth.
Mon Nov 15 00:00:00 EST 2021
TMT-Based Plasma Proteomics Reveals Dyslipidemia Among Lowlanders During Prolonged Stay at High Altitudes.
Frontiers in physiology
Sharma V,Meena RN,Ray K,Panjwani U,Varshney R,Sethy NK
MA5-16308 was used in Western Blotting to demonstrate that long-term stay at high altitudes exacerbates dyslipidemia and associated disorders.
Tue Nov 02 00:00:00 EDT 2021
Overcoming Culture Restriction for SARS-CoV-2 in Human Cells Facilitates the Screening of Compounds Inhibiting Viral Replication.
Antimicrobial agents and chemotherapy
Ramirez S,Fernandez-Antunez C,Galli A,Underwood A,Pham LV,Ryberg LA,Feng S,Pedersen MS,Mikkelsen LS,Belouzard S,Dubuisson J,Sølund C,Weis N,Gottwein JM,Fahnøe U,Bukh J
MA5-16308 was used in Western Blotting to evaluate SARS-CoV-2 culturing in human cells and its infectivity.
Thu Jun 17 00:00:00 EDT 2021
Overcoming Culture Restriction for SARS-CoV-2 in Human Cells Facilitates the Screening of Compounds Inhibiting Viral Replication.
Antimicrobial agents and chemotherapy
Ramirez S,Fernandez-Antunez C,Galli A,Underwood A,Pham LV,Ryberg LA,Feng S,Pedersen MS,Mikkelsen LS,Belouzard S,Dubuisson J,Sølund C,Weis N,Gottwein JM,Fahnøe U,Bukh J
MA5-16308 was used in Western Blotting to evaluate SARS-CoV-2 culturing in human cells and its infectivity.
Thu Jun 17 00:00:00 EDT 2021
Overcoming Culture Restriction for SARS-CoV-2 in Human Cells Facilitates the Screening of Compounds Inhibiting Viral Replication.
Antimicrobial agents and chemotherapy
Ramirez S,Fernandez-Antunez C,Galli A,Underwood A,Pham LV,Ryberg LA,Feng S,Pedersen MS,Mikkelsen LS,Belouzard S,Dubuisson J,Sølund C,Weis N,Gottwein JM,Fahnøe U,Bukh J
MA5-16308 was used in Western Blotting to evaluate SARS-CoV-2 culturing in human cells and its infectivity.
Thu Jun 17 00:00:00 EDT 2021
Survivin drives tumor-associated macrophage reprogramming: a novel mechanism with potential impact for obesity.
Cellular oncology (Dordrecht)
Benaiges E,Ceperuelo-Mallafré V,Madeira A,Bosch R,Núñez-Roa C,Ejarque M,Maymó-Masip E,Huber-Ruano I,Lejeune M,Vendrell J,Fernández-Veledo S
MA5-16308 was used in ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to indicate that survivin may serve as a molecular link between obesity and cancer and as a novel marker for tumor-associated macrophages.
Sun Aug 01 00:00:00 EDT 2021
Gq/11-dependent regulation of endosomal cAMP generation by parathyroid hormone class B GPCR.
Proceedings of the National Academy of Sciences of the United States of America
White AD,Jean-Alphonse FG,Fang F,Peña KA,Liu S,König GM,Inoue A,Aslanoglou D,Gellman SH,Kostenis E,Xiao K,Vilardaga JP
MA5-16308 was used in Western Blotting to investigate the role of Gq/11 activation by the parathyroid hormone (PTH) type 1 receptor (PTHR) in mediating endosomal cAMP responses.
Tue Mar 31 00:00:00 EDT 2020
Effect of Melatonin on Tau aggregation and Tau-mediated cell surface morphology.
International journal of biological macromolecules
Das R,Balmik AA,Chinnathambi S
MA5-16308 was used in Western Blotting to suggest that Melatonin administration shows mild anti-aggregation and cytoprotective effects.
Mon Jun 01 00:00:00 EDT 2020
Synergistic interactions of PlGF and VEGF contribute to blood-retinal barrier breakdown through canonical NFκB activation.
Experimental cell research
Lennikov A,Mukwaya A,Fan L,Saddala MS,De Falco S,Huang H
MA5-16308 was used in Western Blot, Immunohistochemistry to investigate the role of placental growth factor/vascular endothelial growth factor (PlGF-VEGF) heterodimers involved in the blood-retinal barrier breakdown and the associated mechanism.
Tue Dec 15 00:00:00 EST 2020
Synergistic interactions of PlGF and VEGF contribute to blood-retinal barrier breakdown through canonical NFκB activation.
Experimental cell research
Lennikov A,Mukwaya A,Fan L,Saddala MS,De Falco S,Huang H
MA5-16308 was used in Western Blot, Immunohistochemistry to investigate the role of placental growth factor/vascular endothelial growth factor (PlGF-VEGF) heterodimers involved in the blood-retinal barrier breakdown and the associated mechanism.
Tue Dec 15 00:00:00 EST 2020
Synergistic interactions of PlGF and VEGF contribute to blood-retinal barrier breakdown through canonical NFκB activation.
Experimental cell research
Lennikov A,Mukwaya A,Fan L,Saddala MS,De Falco S,Huang H
MA5-16308 was used in Western Blot, Immunohistochemistry to investigate the role of placental growth factor/vascular endothelial growth factor (PlGF-VEGF) heterodimers involved in the blood-retinal barrier breakdown and the associated mechanism.
Tue Dec 15 00:00:00 EST 2020
Synergistic interactions of PlGF and VEGF contribute to blood-retinal barrier breakdown through canonical NFκB activation.
Experimental cell research
Lennikov A,Mukwaya A,Fan L,Saddala MS,De Falco S,Huang H
MA5-16308 was used in Western Blot, Immunohistochemistry to investigate the role of placental growth factor/vascular endothelial growth factor (PlGF-VEGF) heterodimers involved in the blood-retinal barrier breakdown and the associated mechanism.
Tue Dec 15 00:00:00 EST 2020
Precision cut lung slices: a novel versatile tool to examine host-pathogen interaction in the chicken lung.
Veterinary research
Bryson KJ,Garrido D,Esposito M,McLachlan G,Digard P,Schouler C,Guabiraba R,Trapp S,Vervelde L
Published figure using beta Tubulin Loading Control monoclonal antibody (Product # MA5-16308) in Immunohistochemistry
Fri Jan 10 00:00:00 EST 2020
Precision cut lung slices: a novel versatile tool to examine host-pathogen interaction in the chicken lung.
Veterinary research
Bryson KJ,Garrido D,Esposito M,McLachlan G,Digard P,Schouler C,Guabiraba R,Trapp S,Vervelde L
Published figure using beta Tubulin Loading Control monoclonal antibody (Product # MA5-16308) in Immunohistochemistry
Fri Jan 10 00:00:00 EST 2020
Derivation of induced pluripotent stem cells (SDUKIi003-A) from a 20-year-old male patient diagnosed with Asperger syndrome.
Stem cell research
Kamand M,Ilieva M,Louise Forsberg S,Thomassen M,Meyer M,Fex Svenningsen Å,Maria Michel T
MA5-16308 was used in In vitro Assay to validate the expression of pluripotency markers, differentiation into the three germ layers, and absence of chromosomal abnormalities.
Thu Oct 01 00:00:00 EDT 2020
Generation of human induced pluripotent stem cells (SDUKIi002-A) from a 22-year-old male diagnosed with autism spectrum disorder.
Stem cell research
Kamand M,Ilieva M,Forsberg SL,Thomassen M,Fex Svenningsen Å,Holst B,Meyer M,Michel TM
MA5-16308 was used in Immunocytochemistry to create and characterise a human-induced pluripotent stem cell line (SDUKIi002-A) from a 22-year old autistic male identified in the "FYNEN-cohort" of Southern Denmark.
Wed Jul 01 00:00:00 EDT 2020
Generation of human induced pluripotent stem cells (SDUKIi002-A) from a 22-year-old male diagnosed with autism spectrum disorder.
Stem cell research
Kamand M,Ilieva M,Forsberg SL,Thomassen M,Fex Svenningsen Å,Holst B,Meyer M,Michel TM
MA5-16308 was used in Immunocytochemistry to create and characterise a human-induced pluripotent stem cell line (SDUKIi002-A) from a 22-year old autistic male identified in the "FYNEN-cohort" of Southern Denmark.
Wed Jul 01 00:00:00 EDT 2020
High levels of MESP1 expression in non-small cell lung cancer can facilitate cell proliferation, metastasis and suppresses cell apoptosis.
Translational cancer research
Wang L,Yang C,Li F,Mu D,Ran P,Shen H,Li W,Ma J,Wu J,Yang X,Sheng X,Zhu B,Zheng S
Published figure using beta Tubulin Loading Control monoclonal antibody (Product # MA5-16308) in Western Blot
Thu Oct 01 00:00:00 EDT 2020
High levels of MESP1 expression in non-small cell lung cancer can facilitate cell proliferation, metastasis and suppresses cell apoptosis.
Translational cancer research
Wang L,Yang C,Li F,Mu D,Ran P,Shen H,Li W,Ma J,Wu J,Yang X,Sheng X,Zhu B,Zheng S
Published figure using beta Tubulin Loading Control monoclonal antibody (Product # MA5-16308) in Western Blot
Thu Oct 01 00:00:00 EDT 2020
Royal jelly attenuates metabolic defects in a Drosophila mutant with elevated TORC1 activity.
Biology open
Cheng Y,Cai J,Fu Y,Feng C,Hao Y,Wei Y
MA5-16308 was used in Western Blotting to determine the effect royal jelly has on the metabolic function of nprl3 Drosophila mutants.
Fri Nov 06 00:00:00 EST 2020
Royal jelly attenuates metabolic defects in a Drosophila mutant with elevated TORC1 activity.
Biology open
Cheng Y,Cai J,Fu Y,Feng C,Hao Y,Wei Y
MA5-16308 was used in Western Blotting to determine the effect royal jelly has on the metabolic function of nprl3 Drosophila mutants.
Fri Nov 06 00:00:00 EST 2020
Generation of autism spectrum disorder patient-derived iPSC line SDUKIi004-A.
Stem cell research
Kamand M,Ilieva M,Forsberg SL,Thomassen M,Svenningsen ÅF,Meyer M,Michel TM
MA5-16308 was used in Immunocytochemistry-immunofluorescence to try and yield new understanding about underlying neuropathological processes in autism using stem cells which may be essential for drug development.
Tue Dec 01 00:00:00 EST 2020
Treatment with galectin-1 improves myogenic potential and membrane repair in dysferlin-deficient models.
PloS one
Vallecillo-Zúniga ML,Rathgeber MF,Poulson PD,Hayes S,Luddington JS,Gill HN,Teynor M,Kartchner BC,Valdoz J,Stowell C,Markham AR,Arthur C,Stowell S,Van Ry PM
MA5-16308 was used in Western Blotting to reveal Gal-1 mediates disease pathologies through both changes in integral myogenic protein expression and mechanical membrane stabilization.
Tue Oct 27 00:00:00 EDT 2020
Global proteomic analysis of insulin receptor interactors in glomerular podocytes.
Wellcome open research
Hosawi SB,Humphries JD,Coward RJ,Knight D,Humphries MJ,Lennon R
MA5-16308 was used in Western Blotting to define the literature-based insulin receptor (INSR) interactome and utilised an unbiased proteomic approach to examine INSR interactors in podocytes.
Wed Mar 02 00:00:00 EST 2022
Hypoxia Promotes Syndecan-3 Expression in the Tumor Microenvironment.
Frontiers in immunology
Prieto-Fernández E,Egia-Mendikute L,Bosch A,García Del Río A,Jimenez-Lasheras B,Antoñana-Vildosola A,Lee SY,Palazon A
MA5-16308 was used in Western Blotting to investigate the expression of syndecan-3 in several cancer types and the role of hypoxia in this.
Mon Jun 14 00:00:00 EDT 2021
Melatonin Reduces GSK3β-Mediated Tau Phosphorylation, Enhances Nrf2 Nuclear Translocation and Anti-Inflammation.
ASN neuro
Das R,Balmik AA,Chinnathambi S
MA5-16308 was used in Western Blotting to check the neuroprotective function of Melatonin by MTT and LDH assay, where Melatonin inhibited the Tau aggregates-mediated cytotoxicity and membrane leakage in Neuro2A cells.
Wed Oct 06 00:00:00 EDT 2021
Elevated WBP2 Expression in HER2-positive Breast Cancers Correlates with Sensitivity to Trastuzumab-based Neoadjuvant Therapy: A Retrospective and Multicentric Study.
Clinical cancer research : an official journal of the American Association for Cancer Research
Kang SA,Guan JS,Tan HJ,Chu T,Thike AA,Bernadó C,Arribas J,Wong CY,Tan PH,Gudi M,Putti TC,Sohn J,Lim SH,Lee SC,Lim YP
MA5-16308-1MG was used in Western Blotting to investigate whether chronic undernutrition and environmental enteric dysfunction are also associated with altered Ig recognition of the microbiota in children, using two geographically distinct populations from the Afribiota study.
Mon Apr 15 00:00:00 EDT 2019
Genetic Ablation of the Cystine Transporter xCT in PDAC Cells Inhibits mTORC1, Growth, Survival, and Tumor Formation via Nutrient and Oxidative Stresses.
Cancer research
Daher B,Parks SK,Durivault J,Cormerais Y,Baidarjad H,Tambutte E,Pouysségur J,Vučetić M
MA5-16308 was used in Western Blotting to show the cystine/glutamate exchanger xCT is essential for amino acid and redox homeostasis and its inhibition has potential for anticancer therapy by inducing ferroptosis.
Thu Aug 01 00:00:00 EDT 2019
Fetal Gene Therapy Using a Single Injection of Recombinant AAV9 Rescued SMA Phenotype in Mice.
Molecular therapy : the journal of the American Society of Gene Therapy
Rashnonejad A,Amini Chermahini G,Gündüz C,Onay H,Aykut A,Durmaz B,Baka M,Su Q,Gao G,Özkınay F
MA5-16308 was used in Western Blot to investigate the efficacy of human survival motor neuron gene expression after intrauterine delivery in spinal muscular atrophy mouse embryos.
Wed Dec 04 00:00:00 EST 2019
Collagen XIII-derived ectodomain regulates bone angiogenesis and intracortical remodeling.
Matrix biology : journal of the International Society for Matrix Biology
Koivunen J,Kemppainen AV,Finnilä MA,Keski-Filppula R,Härönen H,Tu H,Pellikka H,Heikkinen A,Kylmäoja E,Sormunen R,Miinalainen I,Saarakkala S,Izzi V,Pihlajaniemi T
MA5-16308 was used in Western Blotting to investigate the regulatory role of ColXIII in bone remodeling and ColXIII upregulation in osteoporotic patients.
Tue Oct 01 00:00:00 EDT 2019
Genome-wide effect of pulmonary airway epithelial cell-specific Bmal1 deletion.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Zhang Z,Hunter L,Wu G,Maidstone R,Mizoro Y,Vonslow R,Fife M,Hopwood T,Begley N,Saer B,Wang P,Cunningham P,Baxter M,Durrington H,Blaikley JF,Hussell T,Rattray M,Hogenesch JB,Gibbs J,Ray DW,Loudon ASI
MA5-16308 was used in Western Blotting to find that metabolic cues dictate phasing of the pulmonary clock and circadian responses to immunologic challenges.
Wed May 01 00:00:00 EDT 2019
Exploring the Mitochondrial Degradome by the TAILS Proteomics Approach in a Cellular Model of Parkinson's Disease.
Frontiers in aging neuroscience
Lualdi M,Ronci M,Zilocchi M,Corno F,Turilli ES,Sponchiado M,Aceto A,Alberio T,Fasano M
MA5-16308 was used in Western Blotting to study mitochondrial dysfunction due to dopamine imbalances in Parkinson's Disease.
Wed Sep 30 00:00:00 EDT 2020
Inhibition of the amino-acid transporter LAT1 demonstrates anti-neoplastic activity in medulloblastoma.
Journal of cellular and molecular medicine
Cormerais Y,Pagnuzzi-Boncompagni M,Schrötter S,Giuliano S,Tambutté E,Endou H,Wempe MF,Pagès G,Pouysségur J,Picco V
MA5-16308 was used in Western Blotting to investigate the therapeutic potential of JPH203, a LAT1-specific pharmacological inhibitor, on two independent medulloblastoma cell lines belonging to subgroups 3 and Shh.
Mon Apr 01 00:00:00 EDT 2019
In Preclinical Model of Ovarian Cancer, the SGK1 Inhibitor SI113 Counteracts the Development of Paclitaxel Resistance and Restores Drug Sensitivity.
Translational oncology
D'Antona L,Dattilo V,Catalogna G,Scumaci D,Fiumara CV,Musumeci F,Perrotti G,Schenone S,Tallerico R,Spoleti CB,Costa N,Iuliano R,Cuda G,Amato R,Perrotti N
Published figure using beta Tubulin Loading Control monoclonal antibody (Product # MA5-16308) in Western Blot
Thu Aug 01 00:00:00 EDT 2019
Claudin-19 mediates the effects of NO on the paracellular pathway in thick ascending limbs.
American journal of physiology. Renal physiology
Monzon CM,Garvin JL
MA5-16308 was used in Western Blotting to investigate how claudin-19 effects paracellular signalling in thick ascending limbs.
Thu Aug 01 00:00:00 EDT 2019
Irisin Exerts Inhibitory Effect on Adipogenesis Through Regulation of Wnt Signaling.
Frontiers in physiology
Ma EB,Sahar NE,Jeong M,Huh JY
MA5-16308 was used in Western Blotting to study the expression and secretion pattern of irisin during adipocyte differentiation and the role of irisin in the adipogenic process.
Thu Oct 01 00:00:00 EDT 2020
HtrA4 Protease Promotes Chemotherapeutic-Dependent Cancer Cell Death.
Cells
Wenta T,Rychlowski M,Jarzab M,Lipinska B
Published figure using beta Tubulin Loading Control monoclonal antibody (Product # MA5-16308) in Western Blot
Fri Sep 20 00:00:00 EDT 2019
Sensory innervation in porous endplates by Netrin-1 from osteoclasts mediates PGE2-induced spinal hypersensitivity in mice.
Nature communications
Ni S,Ling Z,Wang X,Cao Y,Wu T,Deng R,Crane JL,Skolasky R,Demehri S,Zhen G,Jain A,Wu P,Pan D,Hu B,Lyu X,Li Y,Chen H,Qi H,Guan Y,Dong X,Wan M,Zou X,Lu H,Hu J,Cao X
Published figure using beta Tubulin Loading Control monoclonal antibody (Product # MA5-16308) in Western Blot
Tue Dec 10 00:00:00 EST 2019
Neuraminidase 1-mediated desialylation of the mucin 1 ectodomain releases a decoy receptor that protects against Pseudomonas aeruginosa lung infection.
The Journal of biological chemistry
Lillehoj EP,Guang W,Hyun SW,Liu A,Hegerle N,Simon R,Cross AS,Ishida H,Luzina IG,Atamas SP,Goldblum SE
MA5-16308 was used in ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to investigate MUC1-ED desialylation in lung infection.
Fri Jan 11 00:00:00 EST 2019
A Genome-wide CRISPR Screen Identifies ZCCHC14 as a Host Factor Required for Hepatitis B Surface Antigen Production.
Cell reports
Hyrina A,Jones C,Chen D,Clarkson S,Cochran N,Feucht P,Hoffman G,Lindeman A,Russ C,Sigoillot F,Tsang T,Uehara K,Xie L,Ganem D,Holdorf M
MA5-16308 was used in Western Blotting to describe a genome-wide CRISPR screen to identify other potential host factors required for HBsAg expression and to gain further insights into the mechanism of RG7834.
Tue Dec 03 00:00:00 EST 2019
GRP78 translocation to the cell surface and O-GlcNAcylation of VE-Cadherin contribute to ER stress-mediated endothelial permeability.
Scientific reports
Lenin R,Nagy PG,Jha KA,Gangaraju R
MA5-16308 was used in Western Blot to test the hypothesis that increased ER stress via O-GlcNAcylation of VE-Cadherin likely contribute to endothelial permeability.
Thu Jul 25 00:00:00 EDT 2019
Modulation of Autophagy by a Small Molecule Inverse Agonist of ERRα Is Neuroprotective.
Frontiers in molecular neuroscience
Suresh SN,Chavalmane AK,Pillai M,Ammanathan V,Vidyadhara DJ,Yarreiphang H,Rai S,Paul A,Clement JP,Alladi PA,Manjithaya R
MA5-16308 was used in Western Blotting to study the role of Oestrogen Related Receptor α in regulating autophagy flux.
Wed Aug 16 00:00:00 EDT 2023
Antinociceptive effect of Valeriana fauriei regulates BDNF signaling in an animal model of fibromyalgia.
International journal of molecular medicine
Lee H,Im J,Won H,Kim JY,Kim HK,Kwon JT,Kim YO,Lee S,Cho IH,Lee SW,Kim HJ
MA5-16308 was used in Western Blotting to conclude the mechanism underlying the protective effects of VF as a therapeutic agent against FM may involve the BDNF signaling pathway.
Mon Jan 01 00:00:00 EST 2018
Featured Article: Deterioration of visual function mediated by senescence-associated endoplasmic reticulum stress in inflammatory tie2-TNF mice.
Experimental biology and medicine (Maywood, N.J.)
Lenin R,Nagy PG,Gentry J,Gangaraju R
MA5-16308 was used in Western Blotting to investigate the relationship between endothelial dysfunction, endoplasmic reticulum (ER) stress, and cellular senescence in the development of retinal dysfunction.
Wed Aug 01 00:00:00 EDT 2018
The glutamine transporter ASCT2 (SLC1A5) promotes tumor growth independently of the amino acid transporter LAT1 (SLC7A5).
The Journal of biological chemistry
Cormerais Y,Massard PA,Vucetic M,Giuliano S,Tambutté E,Durivault J,Vial V,Endou H,Wempe MF,Parks SK,Pouyssegur J
MA5-16308 was used in Western Blotting to elucidate ASCT2's pro-tumoral role and indicate the functional coupling model of ASCT2 and LAT1 is not universal across different cancer types.
Fri Feb 23 00:00:00 EST 2018
Downregulation of N-Acetylglucosaminyltransferase GCNT3 by miR-302b-3p Decreases Non-Small Cell Lung Cancer (NSCLC) Cell Proliferation, Migration and Invasion.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Li Q,Ran P,Zhang X,Guo X,Yuan Y,Dong T,Zhu B,Zheng S,Xiao C
MA5-16308 was used in Western Blotting to investigate the functional mechanisms of GCNT3 regulated by microRNAs in NSCLC.
Fri Nov 09 00:00:00 EST 2018
Cancer progression by reprogrammed BCAA metabolism in myeloid leukaemia.
Nature
Hattori A,Tsunoda M,Konuma T,Kobayashi M,Nagy T,Glushka J,Tayyari F,McSkimming D,Kannan N,Tojo A,Edison AS,Ito T
MA5-16308 was used in Western Blotting to show that BCAT1, a cytosolic aminotransferase for the branched-chain amino acids, is aberrantly activated and functionally required for chronic myeloid leukemia.
Thu May 25 00:00:00 EDT 2017
A novel autophagy modulator 6-Bio ameliorates SNCA/α-synuclein toxicity.
Autophagy
Suresh SN,Chavalmane AK,Dj V,Yarreiphang H,Rai S,Paul A,Clement JP,Alladi PA,Manjithaya R
MA516308 was used in western blot to describe the effects of 6-Bio using a preclinical model of Parkinson disease
Mon Jul 03 00:00:00 EDT 2017
The dense-core vesicle maturation protein CCCP-1 binds RAB-2 and membranes through its C-terminal domain.
Traffic (Copenhagen, Denmark)
Cattin-Ortolá J,Topalidou I,Dosey A,Merz AJ,Ailion M
MA5-16308 was used in Western Blotting to identify the CCCP-1 domains important for its localisation, binding to RAB-2, and function in dense-core vesicle biogenesis.
Wed Nov 01 00:00:00 EDT 2017
Inhibition of PirB Activity by TAT-PEP Improves Mouse Motor Ability and Cognitive Behavior.
Frontiers in aging neuroscience
Mi YJ,Chen H,Guo N,Sun MY,Zhao ZH,Gao XC,Wang XL,Zhang RS,Zhou JB,Gou XC
Fri Aug 04 00:00:00 EDT 2023
Inhibition of PirB Activity by TAT-PEP Improves Mouse Motor Ability and Cognitive Behavior.
Frontiers in aging neuroscience
Mi YJ,Chen H,Guo N,Sun MY,Zhao ZH,Gao XC,Wang XL,Zhang RS,Zhou JB,Gou XC
Fri Aug 04 00:00:00 EDT 2023
A START-domain-containing protein is a novel marker of nervous system components of the sea cucumber Holothuria glaberrima.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology
Rosado-Olivieri EA,Ramos-Ortiz GA,Hernández-Pasos J,Díaz-Balzac CA,Vázquez-Rosa E,Valentín-Tirado G,Vega IE,García-Arrarás JE
MA5-16308 was used in Western Blotting to determine the antigen recognised by the RN1 antibody in the nervous system of Holothuria glaberrima.
Fri Dec 01 00:00:00 EST 2017
Gold nanoclusters-assisted delivery of NGF siRNA for effective treatment of pancreatic cancer.
Nature communications
Lei Y,Tang L,Xie Y,Xianyu Y,Zhang L,Wang P,Hamada Y,Jiang K,Zheng W,Jiang X
Published figure using beta Tubulin Loading Control monoclonal antibody (Product # MA5-16308) in Western Blot
Tue Apr 25 00:00:00 EDT 2017
Dopamine negatively modulates the NCA ion channels in C. elegans.
PLoS genetics
Topalidou I,Cooper K,Pereira L,Ailion M
MA5-16308 was used in Western Blotting to identify a pathway by which dopamine modulates the activity of the NCA channels in Caenorhabditis elegans.
Sun Oct 01 00:00:00 EDT 2017
H2S and homocysteine control a novel feedback regulation of cystathionine beta synthase and cystathionine gamma lyase in cardiomyocytes.
Scientific reports
Nandi SS,Mishra PK
MA5-16308 was used in Western Blotting to study whether homocysteine and hydrogen sulphide regulate cystathionine beta synthase (CBS) and cystathionine gamma lyase (CSE) expression in cardiomyocytes, and CBS deficiency induces cardiac CSE expression.
Fri Jun 16 00:00:00 EDT 2017
Genetic Disruption of the Multifunctional CD98/LAT1 Complex Demonstrates the Key Role of Essential Amino Acid Transport in the Control of mTORC1 and Tumor Growth.
Cancer research
Cormerais Y,Giuliano S,LeFloch R,Front B,Durivault J,Tambutté E,Massard PA,de la Ballina LR,Endou H,Wempe MF,Palacin M,Parks SK,Pouyssegur J
MA5-16308 was used in western blot to demonstrate the key role of essential amino acid transport in the control of mTORC1 and tumor growth caused by genetic disruption of the multifunctional CD98/LAT1 complex
Mon Aug 01 00:00:00 EDT 2016
The EARP Complex and Its Interactor EIPR-1 Are Required for Cargo Sorting to Dense-Core Vesicles.
PLoS genetics
Topalidou I,Cattin-Ortolá J,Pappas AL,Cooper K,Merrihew GE,MacCoss MJ,Ailion M
MA5-16308 was used in western blot to investigate the requirement for EIPR-1 and the EARP complex for cargo sorting to dense-core vesicles
Sun May 01 00:00:00 EDT 2016
Early adaptive response of the retina to a pro-diabetogenic diet: Impairment of cone response and gene expression changes in high-fructose fed rats.
Experimental eye research
Thierry M,Pasquis B,Buteau B,Fourgeux C,Dembele D,Leclere L,Gambert-Nicot S,Acar N,Bron AM,Creuzot-Garcher CP,Bretillon L
MA5-16308 was used in western blot to study the adaptive response of the retina to short-term high fructose treatment
Mon Jun 01 00:00:00 EDT 2015
Prion-like propagation of human brain-derived alpha-synuclein in transgenic mice expressing human wild-type alpha-synuclein.
Acta neuropathologica communications
Bernis ME,Babila JT,Breid S,Wüsten KA,Wüllner U,Tamgüney G
Published figure using beta Tubulin Loading Control monoclonal antibody (Product # MA5-16308) in Western Blot
Thu Nov 26 00:00:00 EST 2015
STAT1 activation by venous malformations mutant Tie2-R849W antagonizes VEGF-A-mediated angiogenic response partly via reduced bFGF production.
Angiogenesis
Huang YH,Wu MP,Pan SC,Su WC,Chen YW,Wu LW
MA5-16308 was used in western blot to study the role of STAT1 in the molecular mechanism of a venous malformation-associated Tie-2 mutation
Tue Jan 01 00:00:00 EST 2013
The pseudophosphatase MK-STYX inhibits stress granule assembly independently of Ser149 phosphorylation of G3BP-1.
The FEBS journal
Barr JE,Munyikwa MR,Frazier EA,Hinton SD
MA5-16308 was used in western blot to study the mechanism by which the pseudophosphatase MK-STYX inhibits the assembly of stress granules
Tue Jan 01 00:00:00 EST 2013
Inositol 1,4,5-trisphosphate receptor regulates replication, differentiation, infectivity and virulence of the parasitic protist Trypanosoma cruzi.
Molecular microbiology
Hashimoto M,Enomoto M,Morales J,Kurebayashi N,Sakurai T,Hashimoto T,Nara T,Mikoshiba K
MA5-16308 was used in western blot to identify and characterize novel Trypanosoma cruzi IP3 receptors and their role in virulence and infectivity
Fri Mar 01 00:00:00 EST 2013
Carvedilol treatment after myocardial infarct decreases cardiomyocytic apoptosis in the peri-infarct zone during cardioplegia-induced cardiac arrest.
Shock (Augusta, Ga.)
Yeh CH,Chen TP,Wang YC,Lin YM,Fang SW
MA5-16308 was used in western blot to study the protective effects of carvedilol against cardiomyocyte apoptosis in a model of hypoxia-reperfusion injury
Mon Apr 01 00:00:00 EDT 2013
Opposite effects of a high-fat diet and calorie restriction on ciliary neurotrophic factor signaling in the mouse hypothalamus.
Frontiers in neuroscience
Severi I,Perugini J,Mondini E,Smorlesi A,Frontini A,Cinti S,Giordano A
Published figure using beta Tubulin Loading Control monoclonal antibody (Product # MA5-16308) in Western Blot
Fri Jan 10 00:00:00 EST 2014
The tyrosine phosphatase PTPN14 is a negative regulator of YAP activity.
PloS one
Michaloglou C,Lehmann W,Martin T,Delaunay C,Hueber A,Barys L,Niu H,Billy E,Wartmann M,Ito M,Wilson CJ,Digan ME,Bauer A,Voshol H,Christofori G,Sellers WR,Hofmann F,Schmelzle T
MA5-16308 was used in western blot to study the mechanism by which PTPN14 modulates YAP activity and the significance for oncogenesis
Thu Nov 14 00:00:00 EST 2013
Oxidative stress, Nrf2 and keratin up-regulation associate with Mallory-Denk body formation in mouse erythropoietic protoporphyria.
Hepatology (Baltimore, Md.)
Singla A,Moons DS,Snider NT,Wagenmaker ER,Jayasundera VB,Omary MB
MA5-16308 was used in western blot to study the use of mutant fch/fch mice as a model of Mallory-Denk body formation
Sun Jul 01 00:00:00 EDT 2012
Indirubin, an acting component of indigo naturalis, inhibits EGFR activation and EGF-induced CDC25B gene expression in epidermal keratinocytes.
Journal of dermatological science
Hsieh WL,Lin YK,Tsai CN,Wang TM,Chen TY,Pang JH
MA5-16308 was used in western blot to study the role of EGFR and CDC25B in the mechanism by which indirubin inhibits epidermal keratinicyte proliferation
Wed Aug 01 00:00:00 EDT 2012
MicroRNA-27a regulates cardiomyocytic apoptosis during cardioplegia-induced cardiac arrest by targeting interleukin 10-related pathways.
Shock (Augusta, Ga.)
Yeh CH,Chen TP,Wang YC,Lin YM,Fang SW
MA5-16308 was used in western blot to study the involvement of microRNA-27a in the apoptosis of cardiomyocytes in response to cardioplegic cardiac arrest during cardiopulmonary bypass
Sat Dec 01 00:00:00 EST 2012
DNA methyltransferase 1, cytosine methylation, and cytosine hydroxymethylation in mammalian mitochondria.
Proceedings of the National Academy of Sciences of the United States of America
Shock LS,Thakkar PV,Peterson EJ,Moran RG,Taylor SM
MA5-16308 was used in western blot to study the role of mitochondrial DNA methyltransferase-1 in the cytosine methylation of mitochondrial DNA
Tue Mar 01 00:00:00 EST 2011
Interdependence of platelet-derived growth factor and estrogen-signaling pathways in inducing neonatal rat testicular gonocytes proliferation.
Biology of reproduction
Thuillier R,Mazer M,Manku G,Boisvert A,Wang Y,Culty M
MA5-16308 was used in western blot to study the interdependence of PDGF and estrogen signaling and their role in gonocyte development
Sat May 01 00:00:00 EDT 2010
Constitutive overexpression of CDC25A in primary human mammary epithelial cells results in both defective DNA damage response and chromosomal breaks at fragile sites.
International journal of cancer
Cangi MG,Piccinin S,Pecciarini L,Talarico A,Dal Cin E,Grassi S,Grizzo A,Maestro R,Doglioni C
MA5-16308 was used in western blot to study the role of CDC25A phosphatase overexpression in promoting genomic instability in primary human mammary epithelial cells
Mon Sep 15 00:00:00 EDT 2008
Efficient coupling of Sec23-Sec24 to Sec13-Sec31 drives COPII-dependent collagen secretion and is essential for normal craniofacial development.
Journal of cell science
Townley AK,Feng Y,Schmidt K,Carter DA,Porter R,Verkade P,Stephens DJ
MA5-16308 was used in western blot to study the role of Sec23-Sec24 coupling to Sec13-Sec31 in the export of collagen from the ER and the significance for craniofacial development
Mon Sep 15 00:00:00 EDT 2008
Neural differentiation arrest in embryonal carcinoma cells with forced expression of EWS-FLI1.
Journal of neuro-oncology
Yang Y,Zhang L,Wei Y,Wang H,Fukuma M,Xu H,Xiong W,Zheng J
MA5-16308 was used in western blot to study the role of EWS-FLI1 in neural differentiation and tumorigenesis
Sat Nov 01 00:00:00 EDT 2008
Growth control of multiple myeloma cells through inhibition of glycogen synthase kinase-3.
Leukemia & lymphoma
Zhou Y,Uddin S,Zimmerman T,Kang JA,Ulaszek J,Wickrema A
MA5-16308 was used in western blot to study the role of GSK-3 in modulating the growth of multiple myeloma cells
Wed Oct 01 00:00:00 EDT 2008
Grape seed extract induces cell cycle arrest and apoptosis in human colon carcinoma cells.
Nutrition and cancer
Kaur M,Mandair R,Agarwal R,Agarwal C
MA5-16308 was used in western blot to study the effects on human colon carcinoma cell growth and apoptosis of grape seed extract
Thu Feb 12 00:00:00 EST 2009
Endothelial nitric oxide synthase in bicuspid aortic valve disease.
The Annals of thoracic surgery
Aicher D,Urbich C,Zeiher A,Dimmeler S,Schäfers HJ
MA5-16308 was used in western blot to study the potential role of eNOS in the pathology of bicuspid aortic valve disease
Sun Apr 01 00:00:00 EDT 2007
Stimulation of non-transferrin iron uptake by iron deprivation in K562 cells.
Blood cells, molecules & diseases
Kovar J,Neubauerova J,Cimburova M,Truksa J,Balusikova K,Horak J
MA5-16308 was used in western blot to study the effect of iron deprivation on the uptake of non-transferrin iron in human erythroleukemia cells
Fri Nov 24 00:00:00 EST 2006
Mechanical stretch induces podocyte hypertrophy in vitro.
Kidney international
Petermann AT,Pippin J,Durvasula R,Pichler R,Hiromura K,Monkawa T,Couser WG,Shankland SJ
MA5-16308 was used in western blot to study the potential role of p21 and p27 in the induction of podocyte hypertrophy by mechanical stretch
Sat Jan 01 00:00:00 EST 2005
Erbin regulates mitogen-activated protein (MAP) kinase activation and MAP kinase-dependent interactions between Merlin and adherens junction protein complexes in Schwann cells.
The Journal of biological chemistry
Rangwala R,Banine F,Borg JP,Sherman LS
MA5-16308 was used in western blot to study the interaction between Merlin and Schwann cell adherens junction proteins and the role of erbin and MAP kinases
Fri Mar 25 00:00:00 EST 2005
TorsinA negatively controls neurite outgrowth of SH-SY5Y human neuronal cell line.
Brain research
Ferrari-Toninelli G,Paccioretti S,Francisconi S,Uberti D,Memo M
MA5-16308 was used in western blot to study the role of torsinA in modulating neurite outgrowth in a human neuronal cell line
Fri Jun 25 00:00:00 EDT 2004
Nicotine strongly activates dendritic cell-mediated adaptive immunity: potential role for progression of atherosclerotic lesions.
Circulation
Aicher A,Heeschen C,Mohaupt M,Cooke JP,Zeiher AM,Dimmeler S
MA5-16308 was used in western blot to study the ability of nicotine to stimulate dendritic cell function and the significance for atherogenesis
Tue Feb 04 00:00:00 EST 2003