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Invitrogen
eIF3g Polyclonal Antibody
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Application
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eIF3g Antibody (PA5-23287) in IHC (P)
Immunohistochemical analysis of eIF3g in formalin-fixed, paraffin-embedded human brain tissue. Samples were incubated in eIF3g polyclonal antibody (Product # PA5-23287) using a dilution of 5 µg/mL. Isotype control (top left) and this antibody (bottom left, right).
Product Details
PA5-23287
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Non-human primate
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A portion of amino acids 50-100 of human eIF3G
Conjugate
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS with 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2540811
Target Information
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. This subunit can bind 18S rRNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: eIF-3 RNA-binding subunit; eIF-3-delta; eIF3 p42; eIF3 p44; eIF3g; Eukaryotic translation initiation factor 3 RNA-binding subunit; Eukaryotic translation initiation factor 3 subunit 4; Eukaryotic translation initiation factor 3 subunit G
Gene Aliases: eIF3-delta; EIF3-P42; eIF3-p44; EIF3G; EIF3S4
UniProt ID: (Human) O75821
Entrez Gene ID: (Human) 8666
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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